The use of dermal antigen testing in predicting the outcome of renal transplantation

The responses to dermal antigen testing to a variety of antigens were measured in patients on regular dialysis. Forty‐eight patients have received renal allografts and graft survival was assessed at 6 months. The antigens used were mumps, monilia, streptokinase/streptodornase, tuberculin and dinitro...

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Veröffentlicht in:British journal of surgery 1981-11, Vol.68 (11), p.784-788
Hauptverfasser: Wedgwood, K. R., Guillou, P. J., Leveson, S. H., Giles, G. R.
Format: Artikel
Sprache:eng
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Zusammenfassung:The responses to dermal antigen testing to a variety of antigens were measured in patients on regular dialysis. Forty‐eight patients have received renal allografts and graft survival was assessed at 6 months. The antigens used were mumps, monilia, streptokinase/streptodornase, tuberculin and dinitrochlorobenzene (DNCB). The responses to these antigens were recorded using standard methodology. The responses failed to correlate with graft survival in these patients when compared singly or in combination. Matching at the HLA‐B locus was also correlated with graft survival. Of 31 patients with a match at this locus, 22 (71 per cent) have functioning grafts at 6 months, compared with only 4 of 13 (31 per cent) of patients with no match at the B locus (P
ISSN:0007-1323
1365-2168
DOI:10.1002/bjs.1800681110