Effects of intraruminal administration of zinc on gastric acid secretion in sheep

Intraruminal administration of zinc sulphate at 100 and 200 mg Zn/kg hodyweight resulted in central and peripheral efTcctsin sheep. Feed intake tvas reduced, pH of the duodenal contents elevated and the secretion of acid from isolated pouches of the abomasum doubled. Suggested explanations include a...

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Veröffentlicht in:	Research in veterinary science 1977-09, Vol.23 (2), p.243-245
Hauptverfasser:	McLeay, L.M., Smith, B.L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Abomasum Abomasum - secretion Acids Animals Duodenum - metabolism Female Gastric juice Gastric Juice - secretion Gastrin Histamine Hydrogen-Ion Concentration Male pH effects Rumen Secretion Sheep Sheep - metabolism Veterinary medicine Zinc Zinc - administration & dosage Zinc - pharmacology Zinc - secretion
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Beschreibung
Zusammenfassung:	Intraruminal administration of zinc sulphate at 100 and 200 mg Zn/kg hodyweight resulted in central and peripheral efTcctsin sheep. Feed intake tvas reduced, pH of the duodenal contents elevated and the secretion of acid from isolated pouches of the abomasum doubled. Suggested explanations include a local inhibitory effect of zinc on abomasal acid secretion elevating duodenal pH and a resultant increased release of gastrin stimulating secretion from the pouches.
ISSN:	0034-5288 1532-2661
DOI:	10.1016/S0034-5288(18)33163-1