Comparative Pharmacokinetics of Coumarin Anticoagulants XXXVI: Predicted Steady-State Patterns of Prothrombin Complex Activity Produced by Equieffective Doses of (R)-(+)- and (S)-(−)-Warfarin in Humans
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| Veröffentlicht in: | Journal of pharmaceutical sciences 1977-12, Vol.66 (12), p.1790-1791 |
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| container_end_page | 1791 |
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| container_issue | 12 |
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| container_title | Journal of pharmaceutical sciences |
| container_volume | 66 |
| creator | Wingard, Lemuel B. Levy, Gerhard |
| description | |
| doi_str_mv | 10.1002/jps.2600661240 |
| format | Article |
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Pharm. Sci</addtitle><subject>(R)-(+)- and (S)-(-)-enantiomers</subject><subject>activity at steady state compared</subject><subject>Anticoagulants-(R)-(+)- and (S)-(-)-warfarin</subject><subject>Anticoagulants—(R)-(+)- and (S)-(−)(-warfarin, activity at steady state compared</subject><subject>Anticoagulants—(R)‐(+)‐ and (S)‐(‐)‐warfarin, activity at steady state compared</subject><subject>Coumarin anticoagulants-warfarin</subject><subject>Coumarin anticoagulants—warfarin, (R)-(+)- and (S)-(−)-enantiomers, steady-state anticoagulant activity compared</subject><subject>Coumarin anticoagulants—warfarin, (R)‐(+)‐ and (S)‐(‐)‐enantiomers, steady‐state anticoagulant activity compared</subject><subject>Humans</subject><subject>Models, Biological</subject><subject>Pharmacokinetics-(R)-(+)- and (S)-(-)-warfarin</subject><subject>Pharmacokinetics—(R)-(+)- and (S)-(−)-warfarin, steady-state anticoagulant activity compared</subject><subject>Pharmacokinetics—(R)‐(+)‐ and (S)‐(‐)‐warfarin, steady‐state anticoagulant activity compared</subject><subject>Prothrombin - metabolism</subject><subject>steady-state anticoagulant activity compared</subject><subject>steadystate anticoagulant activity compared</subject><subject>Stereoisomerism</subject><subject>Time Factors</subject><subject>Warfarin - administration & dosage</subject><subject>Warfarin - metabolism</subject><subject>Warfarin - pharmacology</subject><subject>Warfarin-(R)-(+)- and (S)-(-)-enantiomers</subject><subject>Warfarin—(R)-(+)- and (S)-(−)-enantiomers, steady- state anticoagulant activity compared</subject><subject>Warfarin—(R)‐(+)‐ and (S)‐(‐)‐enantiomers, steadystate anticoagulant activity compared</subject><issn>0022-3549</issn><issn>1520-6017</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1977</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFUc1uEzEYXCH-QuHKiYNPKBHa4N21d7O9hVDaQgsRqWhvltf7mbrNrlPbW5o34Mxr8RY8CV-yVREHhGTJsr-Z8Xgmip4ndJxQmr6-WPlxmlOa50nK6L1okPCUxjlNivvRAAFpnHFWPo6eeH9BEUY5fxQ9LFNe8mwQ_ZzZZiWdDOYayPxcukYqe2laCEZ5YjWZ2a6RzrRk2uKVlV-7pWyDJ2dnZ18Od8ncQW1UgJosAsh6HS-CDKgkQwDXbhXmzoZzZ5sKRTavLeGGTBU-aMJ6M6w7hfRqTfauOgNag9qaeWs9bPnDz6N4-GoUE9nWZLjAw6_vP0bxqXR6awzXAXps_dPogZZLD89u953o5N3eyewgPvq0fzibHsUqYwmNWQkVZzIrWVXLKuWZyjRAkWqtcglVzuoSMKa8KooiL7O0Thmb6GKSTwqdsCTbiV72sitnrzrwQTTGK1hiLmA7L4qsYCXjHIHjHqic9d6BFitnMMy1SKjYdCewO_GnOyS8uFXuqgbqO3hfFo7LfvzNLGH9HzHxfr74SzruucYHuLnjSncpcjTMxenHfcGPjz-wN9lElIif9HjAIK8NOOGVgRabMg4LErU1__rFb-PSyZA</recordid><startdate>197712</startdate><enddate>197712</enddate><creator>Wingard, Lemuel B.</creator><creator>Levy, Gerhard</creator><general>Elsevier Inc</general><general>Wiley Subscription Services, Inc., A Wiley Company</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197712</creationdate><title>Comparative Pharmacokinetics of Coumarin Anticoagulants XXXVI: Predicted Steady-State Patterns of Prothrombin Complex Activity Produced by Equieffective Doses of (R)-(+)- and (S)-(−)-Warfarin in Humans</title><author>Wingard, Lemuel B. ; Levy, Gerhard</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3410-49eb54a394bdab253c3fee72ffc6aeb64d9e0606b7776932d2448f78687f1413</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1977</creationdate><topic>(R)-(+)- and (S)-(-)-enantiomers</topic><topic>activity at steady state compared</topic><topic>Anticoagulants-(R)-(+)- and (S)-(-)-warfarin</topic><topic>Anticoagulants—(R)-(+)- and (S)-(−)(-warfarin, activity at steady state compared</topic><topic>Anticoagulants—(R)‐(+)‐ and (S)‐(‐)‐warfarin, activity at steady state compared</topic><topic>Coumarin anticoagulants-warfarin</topic><topic>Coumarin anticoagulants—warfarin, (R)-(+)- and (S)-(−)-enantiomers, steady-state anticoagulant activity compared</topic><topic>Coumarin anticoagulants—warfarin, (R)‐(+)‐ and (S)‐(‐)‐enantiomers, steady‐state anticoagulant activity compared</topic><topic>Humans</topic><topic>Models, Biological</topic><topic>Pharmacokinetics-(R)-(+)- and (S)-(-)-warfarin</topic><topic>Pharmacokinetics—(R)-(+)- and (S)-(−)-warfarin, steady-state anticoagulant activity compared</topic><topic>Pharmacokinetics—(R)‐(+)‐ and (S)‐(‐)‐warfarin, steady‐state anticoagulant activity compared</topic><topic>Prothrombin - metabolism</topic><topic>steady-state anticoagulant activity compared</topic><topic>steadystate anticoagulant activity compared</topic><topic>Stereoisomerism</topic><topic>Time Factors</topic><topic>Warfarin - administration & dosage</topic><topic>Warfarin - metabolism</topic><topic>Warfarin - pharmacology</topic><topic>Warfarin-(R)-(+)- and (S)-(-)-enantiomers</topic><topic>Warfarin—(R)-(+)- and (S)-(−)-enantiomers, steady- state anticoagulant activity compared</topic><topic>Warfarin—(R)‐(+)‐ and (S)‐(‐)‐enantiomers, steadystate anticoagulant activity compared</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wingard, Lemuel B.</creatorcontrib><creatorcontrib>Levy, Gerhard</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of pharmaceutical sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wingard, Lemuel B.</au><au>Levy, Gerhard</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparative Pharmacokinetics of Coumarin Anticoagulants XXXVI: Predicted Steady-State Patterns of Prothrombin Complex Activity Produced by Equieffective Doses of (R)-(+)- and (S)-(−)-Warfarin in Humans</atitle><jtitle>Journal of pharmaceutical sciences</jtitle><addtitle>J. Pharm. Sci</addtitle><date>1977-12</date><risdate>1977</risdate><volume>66</volume><issue>12</issue><spage>1790</spage><epage>1791</epage><pages>1790-1791</pages><issn>0022-3549</issn><eissn>1520-6017</eissn><cop>Washington</cop><pub>Elsevier Inc</pub><pmid>925953</pmid><doi>10.1002/jps.2600661240</doi><tpages>2</tpages></addata></record> |
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| identifier | ISSN: 0022-3549 |
| ispartof | Journal of pharmaceutical sciences, 1977-12, Vol.66 (12), p.1790-1791 |
| issn | 0022-3549 1520-6017 |
| language | eng |
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| source | MEDLINE; Access via Wiley Online Library; Alma/SFX Local Collection |
| subjects | (R)-(+)- and (S)-(-)-enantiomers activity at steady state compared Anticoagulants-(R)-(+)- and (S)-(-)-warfarin Anticoagulants—(R)-(+)- and (S)-(−)(-warfarin, activity at steady state compared Anticoagulants—(R)‐(+)‐ and (S)‐(‐)‐warfarin, activity at steady state compared Coumarin anticoagulants-warfarin Coumarin anticoagulants—warfarin, (R)-(+)- and (S)-(−)-enantiomers, steady-state anticoagulant activity compared Coumarin anticoagulants—warfarin, (R)‐(+)‐ and (S)‐(‐)‐enantiomers, steady‐state anticoagulant activity compared Humans Models, Biological Pharmacokinetics-(R)-(+)- and (S)-(-)-warfarin Pharmacokinetics—(R)-(+)- and (S)-(−)-warfarin, steady-state anticoagulant activity compared Pharmacokinetics—(R)‐(+)‐ and (S)‐(‐)‐warfarin, steady‐state anticoagulant activity compared Prothrombin - metabolism steady-state anticoagulant activity compared steadystate anticoagulant activity compared Stereoisomerism Time Factors Warfarin - administration & dosage Warfarin - metabolism Warfarin - pharmacology Warfarin-(R)-(+)- and (S)-(-)-enantiomers Warfarin—(R)-(+)- and (S)-(−)-enantiomers, steady- state anticoagulant activity compared Warfarin—(R)‐(+)‐ and (S)‐(‐)‐enantiomers, steadystate anticoagulant activity compared |
| title | Comparative Pharmacokinetics of Coumarin Anticoagulants XXXVI: Predicted Steady-State Patterns of Prothrombin Complex Activity Produced by Equieffective Doses of (R)-(+)- and (S)-(−)-Warfarin in Humans |
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