Comparative Pharmacokinetics of Coumarin Anticoagulants XXXVI: Predicted Steady-State Patterns of Prothrombin Complex Activity Produced by Equieffective Doses of (R)-(+)- and (S)-(−)-Warfarin in Humans

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Veröffentlicht in:	Journal of pharmaceutical sciences 1977-12, Vol.66 (12), p.1790-1791
Hauptverfasser:	Wingard, Lemuel B., Levy, Gerhard
Format:	Artikel
Sprache:	eng
Schlagworte:	(R)-(+)- and (S)-(-)-enantiomers activity at steady state compared Anticoagulants-(R)-(+)- and (S)-(-)-warfarin Anticoagulants—(R)-(+)- and (S)-(−)(-warfarin, activity at steady state compared Anticoagulants—(R)‐(+)‐ and (S)‐(‐)‐warfarin, activity at steady state compared Coumarin anticoagulants-warfarin Coumarin anticoagulants—warfarin, (R)-(+)- and (S)-(−)-enantiomers, steady-state anticoagulant activity compared Coumarin anticoagulants—warfarin, (R)‐(+)‐ and (S)‐(‐)‐enantiomers, steady‐state anticoagulant activity compared Humans Models, Biological Pharmacokinetics-(R)-(+)- and (S)-(-)-warfarin Pharmacokinetics—(R)-(+)- and (S)-(−)-warfarin, steady-state anticoagulant activity compared Pharmacokinetics—(R)‐(+)‐ and (S)‐(‐)‐warfarin, steady‐state anticoagulant activity compared Prothrombin - metabolism steady-state anticoagulant activity compared steadystate anticoagulant activity compared Stereoisomerism Time Factors Warfarin - administration & dosage Warfarin - metabolism Warfarin - pharmacology Warfarin-(R)-(+)- and (S)-(-)-enantiomers Warfarin—(R)-(+)- and (S)-(−)-enantiomers, steady- state anticoagulant activity compared Warfarin—(R)‐(+)‐ and (S)‐(‐)‐enantiomers, steadystate anticoagulant activity compared
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ISSN:	0022-3549 1520-6017
DOI:	10.1002/jps.2600661240