Collaborative Evaluation of a Rat Caries Model in Six Laboratories

Collaborative Evaluation of a Rat Caries Model in Six Laboratories

When highly controlled parallel rat caries studies were run simultaneously in six laboratories, a similar pattern of caries developed in every laboratory with a range in mean values such that the results of no investigator were significantly different from those of at least two others. These results...

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Veröffentlicht in:Journal of dental research 1977-08, Vol.56 (8), p.1007-1012
Hauptverfasser: Larson, R.H., Amsbaugh, S.M., Navia, J.M., Rosen, S., Schuster, G.S., Shaw, J.H.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Dental Caries - etiology
Dentistry
Diet, Cariogenic
Disease Models, Animal
Female
Rats
Research Design
Species Specificity
Streptococcal Infections - complications
Streptococcus mutans
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Zusammenfassung:When highly controlled parallel rat caries studies were run simultaneously in six laboratories, a similar pattern of caries developed in every laboratory with a range in mean values such that the results of no investigator were significantly different from those of at least two others. These results indicate that the major factors influencing development of rat caries have been recognized and can be controlled within reasonable limits.
ISSN:0022-0345
1544-0591
DOI:10.1177/00220345770560080201