Correcting the phenotype of the epidermis from chick embryos homozygous for the gene scaleless (sc/sc) [Mutation]

Correcting the phenotype of the epidermis from chick embryos homozygous for the gene scaleless (sc/sc) [Mutation]

Scutate scales are completely missing in the scaleless (sc/sc) mutant chicken. Organ cultures consisting of epidermis from sc/sc embryos combined with normal (+/+) scale dermis of the same developmental age produce the scaleless phenotype, but the same scaleless epidermis in combination with normal...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 1981-11, Vol.214 (4524), p.1033-1034
Hauptverfasser: McAleese, Susan R., Sawyer, Roger H.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Chick Embryo
Chorioallantoic membrane
Dermis
Diabetes
Epidermis
Feathers - physiology
Foot bones
HeLa cells
Homozygote
Insulin
Parasite hosts
Phenotype
Skin
Skin - embryology
Skin Transplantation
Vertebrates
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Zusammenfassung:Scutate scales are completely missing in the scaleless (sc/sc) mutant chicken. Organ cultures consisting of epidermis from sc/sc embryos combined with normal (+/+) scale dermis of the same developmental age produce the scaleless phenotype, but the same scaleless epidermis in combination with normal dermis from more differentiated embryonic scales forms perfectly normal scales.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.7029712