Regeneration of the Human Endometrium and Presence of Inflammatory Cells Following Diagnostic Curettage

The regeneration of the human endometrium, with particular emphasis on the presence of inflammatory cells, was studied in 106 women undergoing hysterectomy following curettage. The interval between the last curettage and the hysterectomy varied from 1 day to 12 months. A slight but significant increase in the number of neutrophil cells was observed during the first 7 days after the curettage in proliferating endometrium. This increase was considered to reflect the regeneration phenomenon rather than a true infection. No statistically significant increase in the number of neutrophils and mononuclear cells was observed after the first week following the curettage. The study does not provide any evidence that the introduction of a curette or a suction instrument in the uterine cavity increases the risk of endometritis.