Antithrombotic activity of a polydeoxyribonucleotidic substance extracted from mammalian organs: A possible link with prostacyclin

The antithrombotic activity of Fraction P (FP), a polydeoxyribonucleotide extracted from mammalian organs, was studied in different models of experimental thrombosis. FP displays a remarkable protec ting activity against thrombosis induced by collagen (venous thrombosis), electrical stimulation (art...

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Veröffentlicht in:	Thrombosis research 1981-08, Vol.23 (3), p.233-246
Hauptverfasser:	Niada, R, Mantovani, M, Prino, G, Pescador, R, Berti, F, Omini, C, Folco, G.C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Diphosphate - pharmacology Animals Aorta - metabolism Arteries Collagen Colon - metabolism Coronary Vessels - metabolism Cricetinae Electric Stimulation Epoprostenol - biosynthesis Experimental thrombosis Female Fibrinolytic Agents - pharmacology Gastric Mucosa - metabolism Iontophoresis Male Platelet Aggregation - drug effects Polydeoxyribonucleotide as antithrombotic Polydeoxyribonucleotides - pharmacology Prostacyclin-like activity Rabbits Rats Thrombophlebitis - etiology Thrombosis - etiology
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