Temperature dependence of normal sensory nerve action potentials

Sensory conduction velocities of normal subjects are increasing linearly with rising temperature. The duration of the compound sensory action potentials recorded from the median nerve at the wrist and elbow shows a negative temperature coefficient. The peak-to-peak amplitude of these potentials increases from 22 degrees to approximately 26 degrees C and then decreases progressively again up to 36 degrees C. It is believed that this behavior is due to a combination of decreasing temporal dispersion, height and duration of the individual spike potentials.