Bactobolins, Antitumor Antibiotics from Pseudomonas. I. Structures and Antimicrobial Activities

Four anti-tumor antibiotics were isolated from a new strain of Pseudomonas. Two of which were identified as bactobolin and N-acetylbactobolin respectively. The other two constituents, bactobolin B and bactobolin C, were shown to be new compounds and these structures were elucidated from the spectral data and the results of chemical degradation. Antimicrobial activities of these compounds were also discussed.