Increased Incidence of Parenteral Nutrition-Associated Cholestasis with Aminosyn PF Compared to Trophamine
OBJECTIVE: To compare the incidence of parenteral nutrition-associated cholestasis (PNAC) between two pediatric parenteral amino-acid formulations, Aminosyn PF (APF) and Trophamine (TA). STUDY DESIGN: Setting : Tertiary newborn intensive-care nursery. Subjects : A total of 661 neonates who received...
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Veröffentlicht in: | Journal of Perinatology 2003-09, Vol.23 (6), p.444-450 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | OBJECTIVE:
To compare the incidence of parenteral nutrition-associated cholestasis (PNAC) between two pediatric parenteral amino-acid formulations, Aminosyn PF (APF) and Trophamine (TA).
STUDY DESIGN:
Setting
: Tertiary newborn intensive-care nursery.
Subjects
: A total of 661 neonates who received either TA or APF.
Design
: Retrospective. The incidence of PNAC was determined in three groups: Group I (TA, 8/19/97 to 8/19/98,
n
=335), Group II (APF, 8/20/98 to 1/28/99,
n
=157), and Group III (TA, 1/29/99 to 8/1/99,
n
=169).
RESULTS:
No PNAC developed in any infant receiving parenteral nutrition (PN) for |
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ISSN: | 0743-8346 1476-5543 |
DOI: | 10.1038/sj.jp.7210965 |