Increased Incidence of Parenteral Nutrition-Associated Cholestasis with Aminosyn PF Compared to Trophamine

OBJECTIVE: To compare the incidence of parenteral nutrition-associated cholestasis (PNAC) between two pediatric parenteral amino-acid formulations, Aminosyn PF (APF) and Trophamine (TA). STUDY DESIGN: Setting : Tertiary newborn intensive-care nursery. Subjects : A total of 661 neonates who received...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of Perinatology 2003-09, Vol.23 (6), p.444-450
Hauptverfasser: Wright, Kelly, Ernst, Kimberly D, Gaylord, Mark S, Dawson, Joan P, Burnette, Tara M
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:OBJECTIVE: To compare the incidence of parenteral nutrition-associated cholestasis (PNAC) between two pediatric parenteral amino-acid formulations, Aminosyn PF (APF) and Trophamine (TA). STUDY DESIGN: Setting : Tertiary newborn intensive-care nursery. Subjects : A total of 661 neonates who received either TA or APF. Design : Retrospective. The incidence of PNAC was determined in three groups: Group I (TA, 8/19/97 to 8/19/98, n =335), Group II (APF, 8/20/98 to 1/28/99, n =157), and Group III (TA, 1/29/99 to 8/1/99, n =169). RESULTS: No PNAC developed in any infant receiving parenteral nutrition (PN) for
ISSN:0743-8346
1476-5543
DOI:10.1038/sj.jp.7210965