Retrospective diagnosis of congenital cytomegalovirus infection and cortical maldevelopment
Congenital cytomegalovirus (CMV) infection can cause malformations of cortical development (MCD). It is difficult to establish CMV as a cause of MCD several months postpartum. This can now be done by detection of CMV DNA in dried blood spots (DBS test) on Guthrie cards. The authors used DBS tests to...
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Veröffentlicht in: | Neurology 2003-09, Vol.61 (5), p.710-712 |
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container_title | Neurology |
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creator | ZUCCA, C BINDA, S BORGATTI, R TRIULZI, F RADICE, L BUTTE, C BARKHAUS, P. E BARBI, M |
description | Congenital cytomegalovirus (CMV) infection can cause malformations of cortical development (MCD). It is difficult to establish CMV as a cause of MCD several months postpartum. This can now be done by detection of CMV DNA in dried blood spots (DBS test) on Guthrie cards. The authors used DBS tests to assess 10 patients with MCD of unknown cause. Four of the 10 patients were positive for CMV. |
doi_str_mv | 10.1212/wnl.61.5.710 |
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Four of the 10 patients were positive for CMV.</description><identifier>ISSN: 0028-3878</identifier><identifier>EISSN: 1526-632X</identifier><identifier>DOI: 10.1212/wnl.61.5.710</identifier><identifier>PMID: 12963772</identifier><identifier>CODEN: NEURAI</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins</publisher><subject>Biological and medical sciences ; Cerebral Cortex - abnormalities ; Cerebral Cortex - pathology ; Child, Preschool ; Cytomegalovirus Infections - congenital ; Cytomegalovirus Infections - diagnosis ; Female ; Human viral diseases ; Humans ; Infant ; Infectious diseases ; Magnetic Resonance Imaging ; Male ; Medical sciences ; Nervous System Malformations - diagnosis ; Retrospective Studies ; Viral diseases ; Viral diseases of the nervous system</subject><ispartof>Neurology, 2003-09, Vol.61 (5), p.710-712</ispartof><rights>2004 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c383t-63ec2703bc67f25dc60a0b125f09739c27e5a6ad2529331a780d127fd6038dfa3</citedby><cites>FETCH-LOGICAL-c383t-63ec2703bc67f25dc60a0b125f09739c27e5a6ad2529331a780d127fd6038dfa3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=15097097$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12963772$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>ZUCCA, C</creatorcontrib><creatorcontrib>BINDA, S</creatorcontrib><creatorcontrib>BORGATTI, R</creatorcontrib><creatorcontrib>TRIULZI, F</creatorcontrib><creatorcontrib>RADICE, L</creatorcontrib><creatorcontrib>BUTTE, C</creatorcontrib><creatorcontrib>BARKHAUS, P. 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Four of the 10 patients were positive for CMV.</description><subject>Biological and medical sciences</subject><subject>Cerebral Cortex - abnormalities</subject><subject>Cerebral Cortex - pathology</subject><subject>Child, Preschool</subject><subject>Cytomegalovirus Infections - congenital</subject><subject>Cytomegalovirus Infections - diagnosis</subject><subject>Female</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Infant</subject><subject>Infectious diseases</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Nervous System Malformations - diagnosis</subject><subject>Retrospective Studies</subject><subject>Viral diseases</subject><subject>Viral diseases of the nervous system</subject><issn>0028-3878</issn><issn>1526-632X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpF0M1LwzAYBvAgipvTm2fpRU-25mNJ2qMMv2AoiKLgIWT5GJE2qU072X9vhoWdcnh_70ueB4BzBAuEEb759XXBUEELjuABmCKKWc4I_jwEUwhxmZOSlxNwEuM3hGnIq2MwQbhihHM8BV-vpu9CbI3q3cZk2sm1D9HFLNhMBb823vWyztS2D41ZyzpsXDfEzHm72wg-k14n2PVOJdbIWpuNqUPbGN-fgiMr62jOxncG3u_v3haP-fLl4Wlxu8wVKUmfPmsU5pCsFOMWU60YlHCFMLWw4qRKM0MlkxpTXBGCJC-hRphbzSAptZVkBq7-77Zd-BlM7EXjojJ1Lb0JQxScsDmdwyrB63-oUuTYGSvazjWy2woExa5M8fG8FAwJKlKZiV-Md4dVY_Qej-0lcDkCGVN820mvXNw7mgLsMvwBmol-kw</recordid><startdate>20030909</startdate><enddate>20030909</enddate><creator>ZUCCA, C</creator><creator>BINDA, S</creator><creator>BORGATTI, R</creator><creator>TRIULZI, F</creator><creator>RADICE, L</creator><creator>BUTTE, C</creator><creator>BARKHAUS, P. 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E</au><au>BARBI, M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Retrospective diagnosis of congenital cytomegalovirus infection and cortical maldevelopment</atitle><jtitle>Neurology</jtitle><addtitle>Neurology</addtitle><date>2003-09-09</date><risdate>2003</risdate><volume>61</volume><issue>5</issue><spage>710</spage><epage>712</epage><pages>710-712</pages><issn>0028-3878</issn><eissn>1526-632X</eissn><coden>NEURAI</coden><abstract>Congenital cytomegalovirus (CMV) infection can cause malformations of cortical development (MCD). It is difficult to establish CMV as a cause of MCD several months postpartum. This can now be done by detection of CMV DNA in dried blood spots (DBS test) on Guthrie cards. The authors used DBS tests to assess 10 patients with MCD of unknown cause. 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subjects | Biological and medical sciences Cerebral Cortex - abnormalities Cerebral Cortex - pathology Child, Preschool Cytomegalovirus Infections - congenital Cytomegalovirus Infections - diagnosis Female Human viral diseases Humans Infant Infectious diseases Magnetic Resonance Imaging Male Medical sciences Nervous System Malformations - diagnosis Retrospective Studies Viral diseases Viral diseases of the nervous system |
title | Retrospective diagnosis of congenital cytomegalovirus infection and cortical maldevelopment |
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