Etomidate: a valuable anaesthetic for mice

Etomidate: a valuable anaesthetic for mice

Etomidate, a new nonbarbiturate short-acting hypnotic agent, was effective in anaesthetizing laboratory mice at a dose of 23·7 ± 1·5 mg/kg bodyweight ip. Surgical anaesthesia developed which permitted the performance of operations upon the animals for at least 20 minutes after induction, In these mi...

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Veröffentlicht in:Laboratory animals (London) 1981-04, Vol.15 (2), p.151-152
Hauptverfasser: Gomwalk, N E, Healing, T D
Format: Artikel
Sprache:eng
Schlagworte:
Anesthesia, General - veterinary
Animals
Animals, Laboratory
Etomidate - administration & dosage
Imidazoles - administration & dosage
Injections, Intraperitoneal
Mice
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Zusammenfassung:Etomidate, a new nonbarbiturate short-acting hypnotic agent, was effective in anaesthetizing laboratory mice at a dose of 23·7 ± 1·5 mg/kg bodyweight ip. Surgical anaesthesia developed which permitted the performance of operations upon the animals for at least 20 minutes after induction, In these mice (LACA-2 and C57-BL strains), doses up to 33 mg/kg were tolerated. Recovery from anaesthesia was uncomplicated.
ISSN:0023-6772
1758-1117
DOI:10.1258/002367781780959099