Splitting the difference: the germline-somatic mutation debate on generating antibody diversity
In the debate about the mechanism for the generation of immunological diversity, the initial positions of both 'somaticists' and 'germliners' were diametrically opposed. Then, as data developed favoring first one and then the other side, concessions were made, until the final sol...
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Veröffentlicht in: | Nature immunology 2003-09, Vol.4 (9), p.829-833 |
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Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | In the debate about the mechanism for the generation of immunological diversity, the initial positions of both 'somaticists' and 'germliners' were diametrically opposed. Then, as data developed favoring first one and then the other side, concessions were made, until the final solution showed that each had been at least partially correct. |
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ISSN: | 1529-2908 1529-2916 |
DOI: | 10.1038/ni0903-829 |