Adrenal Steroids, Bone Mineral Content and Endometrial Pathology in Postmenopausal Women

Adrenal Steroids, Bone Mineral Content and Endometrial Pathology in Postmenopausal Women

In 19 postmenopausal women, basal serum levels of cortisol, unconjugated dehydroepiandrosterone (DHA), dehydroepiandrosterone sulphate (DHAS), testosterone and unconjugated and total estrone were measured both before and during an ACTH test. A positive correlation was found both between basal levels...

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Veröffentlicht in:Acta obstetricia et gynecologica Scandinavica 1981, Vol.60 (3), p.325-326
Hauptverfasser: Brody, S., Carlström, K., Lagrelius, A., Lunell, N. O., Rosenberg, L.
Format: Artikel
Sprache:eng
Schlagworte:
Adrenal Cortex Hormones - blood
Adrenocorticotropic Hormone - pharmacology
Bone and Bones - analysis
Dehydroepiandrosterone - analogs & derivatives
Dehydroepiandrosterone - blood
Dehydroepiandrosterone Sulfate
Endometrium - pathology
Estrone - blood
Female
Forearm - analysis
Humans
Hydrocortisone - blood
Menopause
Middle Aged
Minerals - analysis
Osteoporosis - etiology
Testosterone - blood
Uterine Neoplasms - etiology
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Zusammenfassung:In 19 postmenopausal women, basal serum levels of cortisol, unconjugated dehydroepiandrosterone (DHA), dehydroepiandrosterone sulphate (DHAS), testosterone and unconjugated and total estrone were measured both before and during an ACTH test. A positive correlation was found both between basal levels of DHAS and the DHA response to ACTH, respectively, and trabecular bone mineral content of the distal forearm. A significant correlation was also observed between bone mineral content and precancerous/cancerous states of the uterine epithelium.
ISSN:0001-6349
1600-0412
DOI:10.3109/00016348109158140