Isolation and Identification of a Metabolite of Haloperidol

Isolation and Identification of a Metabolite of Haloperidol

A new metabolite of haloperidol, formed by what is equivalent to the reduction of the carbonyl group to the alcohol, has been identified in human serum, liver, and urine. The isolation and chromatographic behavior of the compound are discussed.

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Veröffentlicht in:Journal of analytical toxicology 1981-05, Vol.5 (3), p.113-117
1. Verfasser: Pape, B E
Format: Artikel
Sprache:eng
Schlagworte:
alcohols
carbonyls
Chromatography, Gas
Haloperidol
Haloperidol - metabolism
Humans
Liver
Mass Spectrometry
Metabolites
Urine
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container_end_page 117
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container_title Journal of analytical toxicology
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creator Pape, B E
description A new metabolite of haloperidol, formed by what is equivalent to the reduction of the carbonyl group to the alcohol, has been identified in human serum, liver, and urine. The isolation and chromatographic behavior of the compound are discussed.
doi_str_mv 10.1093/jat/5.3.113
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identifier ISSN: 0146-4760
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source MEDLINE; Oxford University Press Archive; Alma/SFX Local Collection
subjects alcohols
carbonyls
Chromatography, Gas
Haloperidol
Haloperidol - metabolism
Humans
Liver
Mass Spectrometry
Metabolites
Urine
title Isolation and Identification of a Metabolite of Haloperidol
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