Isolation and Identification of a Metabolite of Haloperidol

Isolation and Identification of a Metabolite of Haloperidol

A new metabolite of haloperidol, formed by what is equivalent to the reduction of the carbonyl group to the alcohol, has been identified in human serum, liver, and urine. The isolation and chromatographic behavior of the compound are discussed.

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Bibliographische Detailangaben
Veröffentlicht in:Journal of analytical toxicology 1981-05, Vol.5 (3), p.113-117
1. Verfasser: Pape, B E
Format: Artikel
Sprache:eng
Schlagworte:
alcohols
carbonyls
Chromatography, Gas
Haloperidol
Haloperidol - metabolism
Humans
Liver
Mass Spectrometry
Metabolites
Urine
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Beschreibung
Zusammenfassung:A new metabolite of haloperidol, formed by what is equivalent to the reduction of the carbonyl group to the alcohol, has been identified in human serum, liver, and urine. The isolation and chromatographic behavior of the compound are discussed.
ISSN:0146-4760
1945-2403
DOI:10.1093/jat/5.3.113