Effect of long-term hypokinesia on monoamine system and antioxidant status of the brain

Effect of long-term hypokinesia on monoamine system and antioxidant status of the brain

Long-term hypokinesia (30 days) was accompanied by activation of the serotoninergic and dopaminergic systems. Exhaustion of the antioxidant system was observed on days 10-30 of immobilization.

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Bibliographische Detailangaben
Veröffentlicht in:Bulletin of experimental biology and medicine 2003-06, Vol.135 (6), p.556-558
Hauptverfasser: Kamskova, Yu G, Pavlova, V I, Popkova, E V, Loktionova, I V, Arkhipenko, Yu V
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Antioxidants - chemistry
Antioxidants - metabolism
Brain - metabolism
Brain Chemistry
Catalase - metabolism
Ceruloplasmin - analysis
Dopamine - analysis
Female
Hypokinesia - metabolism
Lipid Peroxidation
Male
Norepinephrine - analysis
Rats
Rats, Wistar
Serotonin - analysis
Stress, Psychological
Superoxide Dismutase - metabolism
Time Factors
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Beschreibung
Zusammenfassung:Long-term hypokinesia (30 days) was accompanied by activation of the serotoninergic and dopaminergic systems. Exhaustion of the antioxidant system was observed on days 10-30 of immobilization.
ISSN:0007-4888
1573-8221
DOI:10.1023/A:1025473101185