Treatment of pulmonary hemorrhage in childhood systemic lupus erythematosus with mycophenolate mofetil
Systemic lupus erythematosus is a chronic autoimmune disease of unknown etiology with multisystem involvement. Pulmonary hemorrhage is a major life-threatening manifestation in children and adolescents with systemic lupus erythematosus, as well as in adults. Treatment has traditionally been with hig...
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| Veröffentlicht in: | Southern medical journal (Birmingham, Ala.) Ala.), 2003-07, Vol.96 (7), p.705-707 |
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| container_title | Southern medical journal (Birmingham, Ala.) |
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| creator | SAMAD, Ahmed S LINDSLEY, Carol B |
| description | Systemic lupus erythematosus is a chronic autoimmune disease of unknown etiology with multisystem involvement. Pulmonary hemorrhage is a major life-threatening manifestation in children and adolescents with systemic lupus erythematosus, as well as in adults. Treatment has traditionally been with high-dose corticosteroids, with or without the addition of cytotoxic agents. We report the response of a patient with childhood systemic lupus erythematosus with recurrent pulmonary hemorrhage to treatment with mycophenolate mofetil. |
| doi_str_mv | 10.1097/01.SMJ.0000054424.20202.7D |
| format | Article |
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Pulmonary hemorrhage is a major life-threatening manifestation in children and adolescents with systemic lupus erythematosus, as well as in adults. Treatment has traditionally been with high-dose corticosteroids, with or without the addition of cytotoxic agents. We report the response of a patient with childhood systemic lupus erythematosus with recurrent pulmonary hemorrhage to treatment with mycophenolate mofetil.</description><identifier>ISSN: 0038-4348</identifier><identifier>EISSN: 1541-8243</identifier><identifier>DOI: 10.1097/01.SMJ.0000054424.20202.7D</identifier><identifier>PMID: 12940327</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins</publisher><subject>Adolescent ; Biological and medical sciences ; Care and treatment ; Case studies ; Combined Modality Therapy ; Disease Progression ; Drug Therapy, Combination ; Hemorrhage ; Hemorrhage - diagnosis ; Hemorrhage - drug therapy ; Humans ; Hydroxychloroquine - therapeutic use ; Immunosuppressive Agents - therapeutic use ; Infusions, Intravenous ; Lung Diseases - diagnosis ; Lung Diseases - drug therapy ; Lupus erythematosus ; Lupus Erythematosus, Systemic - diagnosis ; Lupus Erythematosus, Systemic - drug therapy ; Lupus Nephritis - diagnosis ; Lupus Nephritis - drug therapy ; Male ; Medical research ; Medical sciences ; Medicine, Experimental ; Methylprednisolone - therapeutic use ; Mycophenolate mofetil ; Mycophenolic Acid - analogs & derivatives ; Mycophenolic Acid - therapeutic use ; Plasmapheresis ; Prednisone - therapeutic use ; Respiration, Artificial ; Risk factors ; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. 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Pulmonary hemorrhage is a major life-threatening manifestation in children and adolescents with systemic lupus erythematosus, as well as in adults. Treatment has traditionally been with high-dose corticosteroids, with or without the addition of cytotoxic agents. We report the response of a patient with childhood systemic lupus erythematosus with recurrent pulmonary hemorrhage to treatment with mycophenolate mofetil.</description><subject>Adolescent</subject><subject>Biological and medical sciences</subject><subject>Care and treatment</subject><subject>Case studies</subject><subject>Combined Modality Therapy</subject><subject>Disease Progression</subject><subject>Drug Therapy, Combination</subject><subject>Hemorrhage</subject><subject>Hemorrhage - diagnosis</subject><subject>Hemorrhage - drug therapy</subject><subject>Humans</subject><subject>Hydroxychloroquine - therapeutic use</subject><subject>Immunosuppressive Agents - therapeutic use</subject><subject>Infusions, Intravenous</subject><subject>Lung Diseases - diagnosis</subject><subject>Lung Diseases - drug therapy</subject><subject>Lupus erythematosus</subject><subject>Lupus Erythematosus, Systemic - diagnosis</subject><subject>Lupus Erythematosus, Systemic - drug therapy</subject><subject>Lupus Nephritis - diagnosis</subject><subject>Lupus Nephritis - drug therapy</subject><subject>Male</subject><subject>Medical research</subject><subject>Medical sciences</subject><subject>Medicine, Experimental</subject><subject>Methylprednisolone - therapeutic use</subject><subject>Mycophenolate mofetil</subject><subject>Mycophenolic Acid - analogs & derivatives</subject><subject>Mycophenolic Acid - therapeutic use</subject><subject>Plasmapheresis</subject><subject>Prednisone - therapeutic use</subject><subject>Respiration, Artificial</subject><subject>Risk factors</subject><subject>Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis</subject><subject>Vascular hemostatic disorders</subject><issn>0038-4348</issn><issn>1541-8243</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkUuPFCEURonROD2tf8EQE91VybMe7iYzOmrGuHBcE4q6dGGoogUqpv-9tN1Jb4a7INycj8A9CL2lpKakbz8QWv_8_q0mxyWFYKJmpFTd3j1DGyoFrTom-HO0IYR3leCiu0LXKf0ueCu75iW6oqwXhLN2g-xjBJ1nWDIOFu9XP4dFxwOeYA4xTnoH2C3YTM6PUwgjToeUYXYG-3W_JgzxkAuqc0jl9NflCc8HE_YTLMHrDHgOFrLzr9ALq32C1-d9i359_vR4-6V6-HH_9fbmoTKCsVxRIjg1De2awdjS4bwn2gg-9pzRYQRrOAgNrSRMDrodjBh64FL3fdMNdmj4Fr0_3buP4c8KKavZJQPe6wXCmlTLZS9ZywpYncCd9qDcYkOO2uxggah9WMC60r6hRPaNFOUdW1Q_wZcaj9N4MvDxFDAxpBTBqn10cxmtokQdNSpCVdGoLhrVf42qvSvhN-dvrMMM4yV69laAd2dAJ6O9jXoxLl04KWXTS8r_AX76p94</recordid><startdate>20030701</startdate><enddate>20030701</enddate><creator>SAMAD, Ahmed S</creator><creator>LINDSLEY, Carol B</creator><general>Lippincott Williams & Wilkins</general><general>Southern Medical Association</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20030701</creationdate><title>Treatment of pulmonary hemorrhage in childhood systemic lupus erythematosus with mycophenolate mofetil</title><author>SAMAD, Ahmed S ; LINDSLEY, Carol B</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c422t-10431c6186bcf4223390ac43d9321bdefc3e4ae75025ba7bc4b9e35a9968bfb63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Adolescent</topic><topic>Biological and medical sciences</topic><topic>Care and treatment</topic><topic>Case studies</topic><topic>Combined Modality Therapy</topic><topic>Disease Progression</topic><topic>Drug Therapy, Combination</topic><topic>Hemorrhage</topic><topic>Hemorrhage - diagnosis</topic><topic>Hemorrhage - drug therapy</topic><topic>Humans</topic><topic>Hydroxychloroquine - therapeutic use</topic><topic>Immunosuppressive Agents - therapeutic use</topic><topic>Infusions, Intravenous</topic><topic>Lung Diseases - diagnosis</topic><topic>Lung Diseases - drug therapy</topic><topic>Lupus erythematosus</topic><topic>Lupus Erythematosus, Systemic - diagnosis</topic><topic>Lupus Erythematosus, Systemic - drug therapy</topic><topic>Lupus Nephritis - diagnosis</topic><topic>Lupus Nephritis - drug therapy</topic><topic>Male</topic><topic>Medical research</topic><topic>Medical sciences</topic><topic>Medicine, Experimental</topic><topic>Methylprednisolone - therapeutic use</topic><topic>Mycophenolate mofetil</topic><topic>Mycophenolic Acid - analogs & derivatives</topic><topic>Mycophenolic Acid - therapeutic use</topic><topic>Plasmapheresis</topic><topic>Prednisone - therapeutic use</topic><topic>Respiration, Artificial</topic><topic>Risk factors</topic><topic>Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis</topic><topic>Vascular hemostatic disorders</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>SAMAD, Ahmed S</creatorcontrib><creatorcontrib>LINDSLEY, Carol B</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Southern medical journal (Birmingham, Ala.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>SAMAD, Ahmed S</au><au>LINDSLEY, Carol B</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Treatment of pulmonary hemorrhage in childhood systemic lupus erythematosus with mycophenolate mofetil</atitle><jtitle>Southern medical journal (Birmingham, Ala.)</jtitle><addtitle>South Med J</addtitle><date>2003-07-01</date><risdate>2003</risdate><volume>96</volume><issue>7</issue><spage>705</spage><epage>707</epage><pages>705-707</pages><issn>0038-4348</issn><eissn>1541-8243</eissn><abstract>Systemic lupus erythematosus is a chronic autoimmune disease of unknown etiology with multisystem involvement. Pulmonary hemorrhage is a major life-threatening manifestation in children and adolescents with systemic lupus erythematosus, as well as in adults. Treatment has traditionally been with high-dose corticosteroids, with or without the addition of cytotoxic agents. We report the response of a patient with childhood systemic lupus erythematosus with recurrent pulmonary hemorrhage to treatment with mycophenolate mofetil.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins</pub><pmid>12940327</pmid><doi>10.1097/01.SMJ.0000054424.20202.7D</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0038-4348 |
| ispartof | Southern medical journal (Birmingham, Ala.), 2003-07, Vol.96 (7), p.705-707 |
| issn | 0038-4348 1541-8243 |
| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Adolescent Biological and medical sciences Care and treatment Case studies Combined Modality Therapy Disease Progression Drug Therapy, Combination Hemorrhage Hemorrhage - diagnosis Hemorrhage - drug therapy Humans Hydroxychloroquine - therapeutic use Immunosuppressive Agents - therapeutic use Infusions, Intravenous Lung Diseases - diagnosis Lung Diseases - drug therapy Lupus erythematosus Lupus Erythematosus, Systemic - diagnosis Lupus Erythematosus, Systemic - drug therapy Lupus Nephritis - diagnosis Lupus Nephritis - drug therapy Male Medical research Medical sciences Medicine, Experimental Methylprednisolone - therapeutic use Mycophenolate mofetil Mycophenolic Acid - analogs & derivatives Mycophenolic Acid - therapeutic use Plasmapheresis Prednisone - therapeutic use Respiration, Artificial Risk factors Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis Vascular hemostatic disorders |
| title | Treatment of pulmonary hemorrhage in childhood systemic lupus erythematosus with mycophenolate mofetil |
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