Treatment of pulmonary hemorrhage in childhood systemic lupus erythematosus with mycophenolate mofetil

Systemic lupus erythematosus is a chronic autoimmune disease of unknown etiology with multisystem involvement. Pulmonary hemorrhage is a major life-threatening manifestation in children and adolescents with systemic lupus erythematosus, as well as in adults. Treatment has traditionally been with hig...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Southern medical journal (Birmingham, Ala.) Ala.), 2003-07, Vol.96 (7), p.705-707
Hauptverfasser:	SAMAD, Ahmed S, LINDSLEY, Carol B
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Biological and medical sciences Care and treatment Case studies Combined Modality Therapy Disease Progression Drug Therapy, Combination Hemorrhage Hemorrhage - diagnosis Hemorrhage - drug therapy Humans Hydroxychloroquine - therapeutic use Immunosuppressive Agents - therapeutic use Infusions, Intravenous Lung Diseases - diagnosis Lung Diseases - drug therapy Lupus erythematosus Lupus Erythematosus, Systemic - diagnosis Lupus Erythematosus, Systemic - drug therapy Lupus Nephritis - diagnosis Lupus Nephritis - drug therapy Male Medical research Medical sciences Medicine, Experimental Methylprednisolone - therapeutic use Mycophenolate mofetil Mycophenolic Acid - analogs & derivatives Mycophenolic Acid - therapeutic use Plasmapheresis Prednisone - therapeutic use Respiration, Artificial Risk factors Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis Vascular hemostatic disorders
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Systemic lupus erythematosus is a chronic autoimmune disease of unknown etiology with multisystem involvement. Pulmonary hemorrhage is a major life-threatening manifestation in children and adolescents with systemic lupus erythematosus, as well as in adults. Treatment has traditionally been with high-dose corticosteroids, with or without the addition of cytotoxic agents. We report the response of a patient with childhood systemic lupus erythematosus with recurrent pulmonary hemorrhage to treatment with mycophenolate mofetil.
ISSN:	0038-4348 1541-8243
DOI:	10.1097/01.SMJ.0000054424.20202.7D