Drug Susceptibility of Trichosporon beigelii Isolated from Urine and Clinical Features of Their Hosts

We investigated of Trichosporon beigelii by a surveillances tudy for two years in the Tokyo Metropolitan Police Hospital. T. beigelii was frequently found in the urine in aged patients with indwelled urethral catheter and in serious stage patients associated with malignancy. T. beigelii was in allc ases isolated from the samples of patients ian hospital stay over 5 days. Minimum inhibitoryc oncentrations (MICs) of anti-fungala gents against T. beigelii were determined by agar-dilutiomn ethod. Fluconazole resistants trains of T. beigeliwie re found by this method. Microscopic examination revealed phagocyted T. beigelii in multinucleated neutrophils in some cases. In conclusion, T. beigelii might be suggested a causative organism of opportunistic infection in urinary diseases.