Permanent axotomy, a model of axonal atrophy and secondary segmental demyelination and remyelination
Permanent axotomy in cats produced by hind limb ablation results in sequential pathological alterations of myelinated fibers of the proximal nerve stump. The changes are like those previously described for human uremic neuropathy and such system atrophies as Friedreich's ataxia; axonal atrophy...
Gespeichert in:
| Veröffentlicht in: | Annals of neurology 1981-06, Vol.9 (6), p.575-583 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 583 |
|---|---|
| container_issue | 6 |
| container_start_page | 575 |
| container_title | Annals of neurology |
| container_volume | 9 |
| creator | Dyck, Peter James Lais, Alfred C. Karnes, Jeannine L. Sparks, Margaret Hunder, Heidi Low, Phillip A. Windebank, Anthony J. |
| description | Permanent axotomy in cats produced by hind limb ablation results in sequential pathological alterations of myelinated fibers of the proximal nerve stump. The changes are like those previously described for human uremic neuropathy and such system atrophies as Friedreich's ataxia; axonal atrophy → myelin wrinkling → nodal lengthening and internodal demyelination → remyelination. |
| doi_str_mv | 10.1002/ana.410090611 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_73583529</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>73583529</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4401-3bf22c896fe8258e2a047aafe2f374ad96d30da0144df1960871f80f5e038e183</originalsourceid><addsrcrecordid>eNp9kM1PwzAMxSMEgjE4ckTqiROFfLVNjxPiS4KBBIhjZBoHCm0zkk6s_z2BTRMnTrb8fn6yHyEHjJ4wSvkpdHAiY1fSnLENMmKZYKnistwkIypymWZMyB2yG8I7jVTO6DbZLnhWMk5HxNyjb6HDrk9g4XrXDscJJK0z2CTO_sw6aBLovZu9DQl0JglYuc6AH2L32sbFqBtsB2zqDvradb-U_zvZI1sWmoD7qzomTxfnj2dX6c3d5fXZ5CatpKQsFS-W80qVuUXFM4UcqCwALHIrCgmmzI2gBiiT0lhW5lQVzCpqM6RCIVNiTI6WvjPvPucYet3WocKmiQ-6edCFyJTIeBnBdAlW3oXg0eqZr9v4k2ZU_6SqY6p6nWrkD1fG85cWzZpexRj1Yql_1Q0O_5vpyXTy13l1SR16XKw3wX_ovBBFpp-nlzqfXoir6e2DFuIbR6KS6g</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>73583529</pqid></control><display><type>article</type><title>Permanent axotomy, a model of axonal atrophy and secondary segmental demyelination and remyelination</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Dyck, Peter James ; Lais, Alfred C. ; Karnes, Jeannine L. ; Sparks, Margaret ; Hunder, Heidi ; Low, Phillip A. ; Windebank, Anthony J.</creator><creatorcontrib>Dyck, Peter James ; Lais, Alfred C. ; Karnes, Jeannine L. ; Sparks, Margaret ; Hunder, Heidi ; Low, Phillip A. ; Windebank, Anthony J.</creatorcontrib><description>Permanent axotomy in cats produced by hind limb ablation results in sequential pathological alterations of myelinated fibers of the proximal nerve stump. The changes are like those previously described for human uremic neuropathy and such system atrophies as Friedreich's ataxia; axonal atrophy → myelin wrinkling → nodal lengthening and internodal demyelination → remyelination.</description><identifier>ISSN: 0364-5134</identifier><identifier>EISSN: 1531-8249</identifier><identifier>DOI: 10.1002/ana.410090611</identifier><identifier>PMID: 7259120</identifier><language>eng</language><publisher>Hoboken: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Animals ; Atrophy ; Axons - pathology ; Axons - surgery ; Cats ; Demyelinating Diseases - physiopathology ; Disease Models, Animal ; Myelin Sheath - physiology ; Nerve Regeneration ; Peripheral Nerves - physiopathology ; Peripheral Nerves - surgery</subject><ispartof>Annals of neurology, 1981-06, Vol.9 (6), p.575-583</ispartof><rights>Copyright © 1981 American Neurological Association</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4401-3bf22c896fe8258e2a047aafe2f374ad96d30da0144df1960871f80f5e038e183</citedby><cites>FETCH-LOGICAL-c4401-3bf22c896fe8258e2a047aafe2f374ad96d30da0144df1960871f80f5e038e183</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fana.410090611$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fana.410090611$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27903,27904,45553,45554</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7259120$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Dyck, Peter James</creatorcontrib><creatorcontrib>Lais, Alfred C.</creatorcontrib><creatorcontrib>Karnes, Jeannine L.</creatorcontrib><creatorcontrib>Sparks, Margaret</creatorcontrib><creatorcontrib>Hunder, Heidi</creatorcontrib><creatorcontrib>Low, Phillip A.</creatorcontrib><creatorcontrib>Windebank, Anthony J.</creatorcontrib><title>Permanent axotomy, a model of axonal atrophy and secondary segmental demyelination and remyelination</title><title>Annals of neurology</title><addtitle>Ann Neurol</addtitle><description>Permanent axotomy in cats produced by hind limb ablation results in sequential pathological alterations of myelinated fibers of the proximal nerve stump. The changes are like those previously described for human uremic neuropathy and such system atrophies as Friedreich's ataxia; axonal atrophy → myelin wrinkling → nodal lengthening and internodal demyelination → remyelination.</description><subject>Animals</subject><subject>Atrophy</subject><subject>Axons - pathology</subject><subject>Axons - surgery</subject><subject>Cats</subject><subject>Demyelinating Diseases - physiopathology</subject><subject>Disease Models, Animal</subject><subject>Myelin Sheath - physiology</subject><subject>Nerve Regeneration</subject><subject>Peripheral Nerves - physiopathology</subject><subject>Peripheral Nerves - surgery</subject><issn>0364-5134</issn><issn>1531-8249</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1981</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kM1PwzAMxSMEgjE4ckTqiROFfLVNjxPiS4KBBIhjZBoHCm0zkk6s_z2BTRMnTrb8fn6yHyEHjJ4wSvkpdHAiY1fSnLENMmKZYKnistwkIypymWZMyB2yG8I7jVTO6DbZLnhWMk5HxNyjb6HDrk9g4XrXDscJJK0z2CTO_sw6aBLovZu9DQl0JglYuc6AH2L32sbFqBtsB2zqDvradb-U_zvZI1sWmoD7qzomTxfnj2dX6c3d5fXZ5CatpKQsFS-W80qVuUXFM4UcqCwALHIrCgmmzI2gBiiT0lhW5lQVzCpqM6RCIVNiTI6WvjPvPucYet3WocKmiQ-6edCFyJTIeBnBdAlW3oXg0eqZr9v4k2ZU_6SqY6p6nWrkD1fG85cWzZpexRj1Yql_1Q0O_5vpyXTy13l1SR16XKw3wX_ovBBFpp-nlzqfXoir6e2DFuIbR6KS6g</recordid><startdate>198106</startdate><enddate>198106</enddate><creator>Dyck, Peter James</creator><creator>Lais, Alfred C.</creator><creator>Karnes, Jeannine L.</creator><creator>Sparks, Margaret</creator><creator>Hunder, Heidi</creator><creator>Low, Phillip A.</creator><creator>Windebank, Anthony J.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198106</creationdate><title>Permanent axotomy, a model of axonal atrophy and secondary segmental demyelination and remyelination</title><author>Dyck, Peter James ; Lais, Alfred C. ; Karnes, Jeannine L. ; Sparks, Margaret ; Hunder, Heidi ; Low, Phillip A. ; Windebank, Anthony J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4401-3bf22c896fe8258e2a047aafe2f374ad96d30da0144df1960871f80f5e038e183</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1981</creationdate><topic>Animals</topic><topic>Atrophy</topic><topic>Axons - pathology</topic><topic>Axons - surgery</topic><topic>Cats</topic><topic>Demyelinating Diseases - physiopathology</topic><topic>Disease Models, Animal</topic><topic>Myelin Sheath - physiology</topic><topic>Nerve Regeneration</topic><topic>Peripheral Nerves - physiopathology</topic><topic>Peripheral Nerves - surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dyck, Peter James</creatorcontrib><creatorcontrib>Lais, Alfred C.</creatorcontrib><creatorcontrib>Karnes, Jeannine L.</creatorcontrib><creatorcontrib>Sparks, Margaret</creatorcontrib><creatorcontrib>Hunder, Heidi</creatorcontrib><creatorcontrib>Low, Phillip A.</creatorcontrib><creatorcontrib>Windebank, Anthony J.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Annals of neurology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dyck, Peter James</au><au>Lais, Alfred C.</au><au>Karnes, Jeannine L.</au><au>Sparks, Margaret</au><au>Hunder, Heidi</au><au>Low, Phillip A.</au><au>Windebank, Anthony J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Permanent axotomy, a model of axonal atrophy and secondary segmental demyelination and remyelination</atitle><jtitle>Annals of neurology</jtitle><addtitle>Ann Neurol</addtitle><date>1981-06</date><risdate>1981</risdate><volume>9</volume><issue>6</issue><spage>575</spage><epage>583</epage><pages>575-583</pages><issn>0364-5134</issn><eissn>1531-8249</eissn><abstract>Permanent axotomy in cats produced by hind limb ablation results in sequential pathological alterations of myelinated fibers of the proximal nerve stump. The changes are like those previously described for human uremic neuropathy and such system atrophies as Friedreich's ataxia; axonal atrophy → myelin wrinkling → nodal lengthening and internodal demyelination → remyelination.</abstract><cop>Hoboken</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>7259120</pmid><doi>10.1002/ana.410090611</doi><tpages>9</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0364-5134 |
| ispartof | Annals of neurology, 1981-06, Vol.9 (6), p.575-583 |
| issn | 0364-5134 1531-8249 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_73583529 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Animals Atrophy Axons - pathology Axons - surgery Cats Demyelinating Diseases - physiopathology Disease Models, Animal Myelin Sheath - physiology Nerve Regeneration Peripheral Nerves - physiopathology Peripheral Nerves - surgery |
| title | Permanent axotomy, a model of axonal atrophy and secondary segmental demyelination and remyelination |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-27T17%3A43%3A21IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Permanent%20axotomy,%20a%20model%20of%20axonal%20atrophy%20and%20secondary%20segmental%20demyelination%20and%20remyelination&rft.jtitle=Annals%20of%20neurology&rft.au=Dyck,%20Peter%20James&rft.date=1981-06&rft.volume=9&rft.issue=6&rft.spage=575&rft.epage=583&rft.pages=575-583&rft.issn=0364-5134&rft.eissn=1531-8249&rft_id=info:doi/10.1002/ana.410090611&rft_dat=%3Cproquest_cross%3E73583529%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=73583529&rft_id=info:pmid/7259120&rfr_iscdi=true |