Angioimmunoblastic lymphadenopathy: A study of the function of lymphocyte populations

The case of a 57‐year‐old woman with the diagnosis of angioimmunoblastic lymphadenopathy (AILD) is reported. During the 15 years of the disease, no malignant transformation had been detected. The clinical picture is unusual in certain respects. Lymph node manifestation had been preceded by extraglan...

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Veröffentlicht in:	Cancer 1981-06, Vol.47 (12), p.2850-2855
Hauptverfasser:	Garam, Tamás, Bak, Mihály, Bakács, Tibor, Döbrentei, Eszter, Petrányi, Győző
Format:	Artikel
Sprache:	eng
Schlagworte:	Biopsy Cytotoxicity, Immunologic Female Humans Immunoblastic Lymphadenopathy - immunology Immunoblastic Lymphadenopathy - pathology Lymphocyte Activation Lymphocytes - immunology Middle Aged T-Lymphocytes - immunology
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Zusammenfassung:	The case of a 57‐year‐old woman with the diagnosis of angioimmunoblastic lymphadenopathy (AILD) is reported. During the 15 years of the disease, no malignant transformation had been detected. The clinical picture is unusual in certain respects. Lymph node manifestation had been preceded by extraglandular AILD infiltrates. All histologic materials showed a picture typical of AILD. A functional study of peripheral lymphocyte subpopulations revealed decreased natural cytotoxicity and decreased T‐lymphocyte activity.
ISSN:	0008-543X 1097-0142
DOI:	10.1002/1097-0142(19810615)47:12<2850::AID-CNCR2820471217>3.0.CO;2-G