Cholesterol ester transfer protein, apolipoprotein E and lipoprotein lipase genotypes in patients with coronary artery disease in the Turkish population

The aim of this study was to compare patients with coronary artery disease (CAD) to healthy objects, in order to explore a possible association between CAD and the variants in the gene encoding cholesterol ester transfer protein (CETP), apolipoprotein E (Apo E) and lipoprotein lipase (LPL). The rela...

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Veröffentlicht in:	Clinical genetics 2003-09, Vol.64 (3), p.228-234
Hauptverfasser:	Isbir, T, Yilmaz, H, Agachan, B, Karaali, ZE
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alleles apolipoprotein E Apolipoproteins E - genetics Biological and medical sciences Cardiology. Vascular system Carrier Proteins - genetics cholesterol ester transfer protein Cholesterol Ester Transfer Proteins Cholesterol, HDL - blood Cholesterol, LDL - blood coronary artery disease Coronary Artery Disease - blood Coronary Artery Disease - epidemiology Coronary Artery Disease - genetics Coronary heart disease Female Genetic Predisposition to Disease Genotype Glycoproteins Heart high-density lipoprotein Humans Hypercholesterolemia - blood Hypercholesterolemia - genetics lipoprotein lipase Lipoprotein Lipase - genetics Male Medical sciences Middle Aged Polymerase Chain Reaction Polymorphism, Restriction Fragment Length Risk Factors Tropical medicine Turkey - epidemiology
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Zusammenfassung:	The aim of this study was to compare patients with coronary artery disease (CAD) to healthy objects, in order to explore a possible association between CAD and the variants in the gene encoding cholesterol ester transfer protein (CETP), apolipoprotein E (Apo E) and lipoprotein lipase (LPL). The relationship between CETP MspI, apo E and LPL PvuII gene polymorphisms and serum lipids were investigated in 173 patients with CAD and 111 healthy controls. The frequency of Apo ε4 (p
ISSN:	0009-9163 1399-0004
DOI:	10.1034/j.1399-0004.2003.00137.x