Mammalian metabolism of phencyclidine

In dogs, the major metabolite of phencyclidine was found to be 5-(N-(1'-phenylcyclohexyl)amino)pentanoic acid (1). The gamma -aminobutyric acid like metabolite was also pharmacologically evaluated to determine if the purported GABA-ergic mediated effects of phencyclidine on locomotor activity m...

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Veröffentlicht in:	Journal of medicinal chemistry 1981-06, Vol.24 (6), p.666-669
Hauptverfasser:	Baker, John K, Wohlford, James G, Bradbury, Barton J, Wirth, Philip W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Dogs gamma-Aminobutyric Acid - pharmacology Male Mice Motor Activity - drug effects Phencyclidine - analogs & derivatives Phencyclidine - metabolism Phencyclidine - pharmacology
Online-Zugang:	Volltext
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