NMR Studies of Structure and Function of Biological Macromolecules (Nobel Lecture)

NMR Studies of Structure and Function of Biological Macromolecules (Nobel Lecture)

The structure of proteins (such as that of bovine prion protein, see picture) and further information on the dynamics and structural, thermodynamic, and kinetic aspects of their interactions with other components in solution can be obtained by NMR methods developed by K. Wüthrich and his group. In h...

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Veröffentlicht in:Angewandte Chemie International Edition 2003-07, Vol.42 (29), p.3340-3363
1. Verfasser: Wüthrich, Kurt
Format: Artikel
Sprache:eng
Schlagworte:
NMR spectroscopy
Nobel lecture
proteins
structure determination
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Beschreibung
Zusammenfassung:The structure of proteins (such as that of bovine prion protein, see picture) and further information on the dynamics and structural, thermodynamic, and kinetic aspects of their interactions with other components in solution can be obtained by NMR methods developed by K. Wüthrich and his group. In his Nobel Lecture, Wüthrich delves into the past, present, and future of these techniques, and offers us a glimpse into his life.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.200300595