Paracetamol and metabolite pharmacokinetics in infants

Paracetamol and metabolite pharmacokinetics in infants

Data concerning metabolism of paracetamol in infants are scant. Previous studies have examined urinary metabolite recovery rates after a single dose of paracetamol in either neonates (

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Bibliographische Detailangaben
Veröffentlicht in:European journal of clinical pharmacology 2003-07, Vol.59 (3), p.243-251
Hauptverfasser: VAN DER MAREL, Caroline D, ANDERSON, Brian J, VAN LINGEN, Richard A, HOLFORD, Nicholas H. G, PLUIM, Marien A. L, JANSMAN, Frank G. A, VAN DEN ANKER, John N, TIBBOEL, Dick
Format: Artikel
Sprache:eng
Schlagworte:
Acetaminophen - analogs & derivatives
Acetaminophen - blood
Acetaminophen - metabolism
Acetaminophen - pharmacokinetics
Acetaminophen - therapeutic use
Acetaminophen - urine
Analgesics
Analgesics, Non-Narcotic - metabolism
Analgesics, Non-Narcotic - pharmacokinetics
Analgesics, Non-Narcotic - therapeutic use
Biological and medical sciences
Female
Humans
Infant
Male
Medical sciences
Metabolic Clearance Rate
Neuropharmacology
Pain, Postoperative - drug therapy
Pharmacology. Drug treatments
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Beschreibung
Zusammenfassung:Data concerning metabolism of paracetamol in infants are scant. Previous studies have examined urinary metabolite recovery rates after a single dose of paracetamol in either neonates (
ISSN:0031-6970
1432-1041
DOI:10.1007/s00228-003-0608-0