Hippuristerones E-I, new polyoxygenated steroids from the gorgonian coral Isis hippuris
Five novel (22R,23S,24S)-steroids, hippuristerones E-I (1-5), have been isolated from the gorgonian coral Isis hippuris. The structures of steroids 1-5 were deduced by extensive 1D and 2D NMR studies ((1)H, (13)C, (1)H-(1)H COSY, HMQC, HMBC, and NOESY experiments). The structure of 1 was further sup...
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| Veröffentlicht in: | Journal of natural products (Washington, D.C.) D.C.), 2003-07, Vol.66 (7), p.917-921 |
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| container_title | Journal of natural products (Washington, D.C.) |
| container_volume | 66 |
| creator | Sheu, J.H Huang, L.F Chen, S.P Yang, Y.L Sung, P.J Wang, G.H Su, J.H Chao, C.H Hu, W.P Wang, J.J |
| description | Five novel (22R,23S,24S)-steroids, hippuristerones E-I (1-5), have been isolated from the gorgonian coral Isis hippuris. The structures of steroids 1-5 were deduced by extensive 1D and 2D NMR studies ((1)H, (13)C, (1)H-(1)H COSY, HMQC, HMBC, and NOESY experiments). The structure of 1 was further supported by molecular mechanics calculations. |
| doi_str_mv | 10.1021/np020602r |
| format | Article |
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The structures of steroids 1-5 were deduced by extensive 1D and 2D NMR studies ((1)H, (13)C, (1)H-(1)H COSY, HMQC, HMBC, and NOESY experiments). The structure of 1 was further supported by molecular mechanics calculations.</description><identifier>ISSN: 0163-3864</identifier><identifier>EISSN: 1520-6025</identifier><identifier>DOI: 10.1021/np020602r</identifier><identifier>PMID: 12880306</identifier><identifier>CODEN: JNPRDF</identifier><language>eng</language><publisher>Washington, DC: American Chemical Society</publisher><subject>Analytical, structural and metabolic biochemistry ; Animals ; Anthozoa - chemistry ; biochemical pathways ; Biological and medical sciences ; biosynthesis ; carbon ; chemical structure ; corals ; Fundamental and applied biological sciences. Psychology ; hippuristerones ; Isis hippuris ; methine ; methylene ; Molecular Conformation ; Molecular Structure ; Nuclear Magnetic Resonance, Biomolecular ; Other biological molecules ; Oxygen - chemistry ; protons ; spectral analysis ; stereochemistry ; steroids ; Steroids - chemistry ; Steroids - isolation & purification ; Taiwan ; Terpenes, steroids. Hormones</subject><ispartof>Journal of natural products (Washington, D.C.), 2003-07, Vol.66 (7), p.917-921</ispartof><rights>2003 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=15025196$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12880306$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sheu, J.H</creatorcontrib><creatorcontrib>Huang, L.F</creatorcontrib><creatorcontrib>Chen, S.P</creatorcontrib><creatorcontrib>Yang, Y.L</creatorcontrib><creatorcontrib>Sung, P.J</creatorcontrib><creatorcontrib>Wang, G.H</creatorcontrib><creatorcontrib>Su, J.H</creatorcontrib><creatorcontrib>Chao, C.H</creatorcontrib><creatorcontrib>Hu, W.P</creatorcontrib><creatorcontrib>Wang, J.J</creatorcontrib><title>Hippuristerones E-I, new polyoxygenated steroids from the gorgonian coral Isis hippuris</title><title>Journal of natural products (Washington, D.C.)</title><addtitle>J. Nat. Prod</addtitle><description>Five novel (22R,23S,24S)-steroids, hippuristerones E-I (1-5), have been isolated from the gorgonian coral Isis hippuris. The structures of steroids 1-5 were deduced by extensive 1D and 2D NMR studies ((1)H, (13)C, (1)H-(1)H COSY, HMQC, HMBC, and NOESY experiments). The structure of 1 was further supported by molecular mechanics calculations.</description><subject>Analytical, structural and metabolic biochemistry</subject><subject>Animals</subject><subject>Anthozoa - chemistry</subject><subject>biochemical pathways</subject><subject>Biological and medical sciences</subject><subject>biosynthesis</subject><subject>carbon</subject><subject>chemical structure</subject><subject>corals</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>hippuristerones</subject><subject>Isis hippuris</subject><subject>methine</subject><subject>methylene</subject><subject>Molecular Conformation</subject><subject>Molecular Structure</subject><subject>Nuclear Magnetic Resonance, Biomolecular</subject><subject>Other biological molecules</subject><subject>Oxygen - chemistry</subject><subject>protons</subject><subject>spectral analysis</subject><subject>stereochemistry</subject><subject>steroids</subject><subject>Steroids - chemistry</subject><subject>Steroids - isolation & purification</subject><subject>Taiwan</subject><subject>Terpenes, steroids. Hormones</subject><issn>0163-3864</issn><issn>1520-6025</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpF0D1PwzAQBmALgaB8DPwB8AITgbMdO_GIqgKVQCDRqqPlxnYbSONgp4L-e1JaYLl7pXt0w4vQKYFrApTc1A1QEEDDDuoRTiHpMt9FPSCCJSwX6QE6jPENABhIvo8OCM3zLosemjyUTbMMZWxt8LWNeJAMr3BtP3Hjq5X_Ws1srVtr8A8oTcQu-AVu5xbPfJj5utQ1LnzQFR7GMuL59t0x2nO6ivZku4_Q-G4w6j8kj8_3w_7tY-KYyNpuAsstSMkcoWCcdjmRpijMNIUpywppjM45l1wbByYtYEo02Iw7cMIQIdkRutz8bYL_WNrYqkUZC1tVurZ-GVXGUsk4px0828LldGGNakK50GGlfqvowMUW6FjoygVdF2X8d7zrlMi1SzZu3dnX312HdyUylnE1enlVlPfpSMCTmnT-fOOd9krPum7U-JUCYUCAS0FT9g0WI4W-</recordid><startdate>20030701</startdate><enddate>20030701</enddate><creator>Sheu, J.H</creator><creator>Huang, L.F</creator><creator>Chen, S.P</creator><creator>Yang, Y.L</creator><creator>Sung, P.J</creator><creator>Wang, G.H</creator><creator>Su, J.H</creator><creator>Chao, C.H</creator><creator>Hu, W.P</creator><creator>Wang, J.J</creator><general>American Chemical Society</general><general>American Society of Pharmacognosy</general><scope>FBQ</scope><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20030701</creationdate><title>Hippuristerones E-I, new polyoxygenated steroids from the gorgonian coral Isis hippuris</title><author>Sheu, J.H ; Huang, L.F ; Chen, S.P ; Yang, Y.L ; Sung, P.J ; Wang, G.H ; Su, J.H ; Chao, C.H ; Hu, W.P ; Wang, J.J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-f367t-f3038e0993f120dfaf819dccdb40b37c9dda85595adf0d4c0b1a0e75f0f6d1693</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Analytical, structural and metabolic biochemistry</topic><topic>Animals</topic><topic>Anthozoa - chemistry</topic><topic>biochemical pathways</topic><topic>Biological and medical sciences</topic><topic>biosynthesis</topic><topic>carbon</topic><topic>chemical structure</topic><topic>corals</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>hippuristerones</topic><topic>Isis hippuris</topic><topic>methine</topic><topic>methylene</topic><topic>Molecular Conformation</topic><topic>Molecular Structure</topic><topic>Nuclear Magnetic Resonance, Biomolecular</topic><topic>Other biological molecules</topic><topic>Oxygen - chemistry</topic><topic>protons</topic><topic>spectral analysis</topic><topic>stereochemistry</topic><topic>steroids</topic><topic>Steroids - chemistry</topic><topic>Steroids - isolation & purification</topic><topic>Taiwan</topic><topic>Terpenes, steroids. Hormones</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sheu, J.H</creatorcontrib><creatorcontrib>Huang, L.F</creatorcontrib><creatorcontrib>Chen, S.P</creatorcontrib><creatorcontrib>Yang, Y.L</creatorcontrib><creatorcontrib>Sung, P.J</creatorcontrib><creatorcontrib>Wang, G.H</creatorcontrib><creatorcontrib>Su, J.H</creatorcontrib><creatorcontrib>Chao, C.H</creatorcontrib><creatorcontrib>Hu, W.P</creatorcontrib><creatorcontrib>Wang, J.J</creatorcontrib><collection>AGRIS</collection><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of natural products (Washington, D.C.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sheu, J.H</au><au>Huang, L.F</au><au>Chen, S.P</au><au>Yang, Y.L</au><au>Sung, P.J</au><au>Wang, G.H</au><au>Su, J.H</au><au>Chao, C.H</au><au>Hu, W.P</au><au>Wang, J.J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hippuristerones E-I, new polyoxygenated steroids from the gorgonian coral Isis hippuris</atitle><jtitle>Journal of natural products (Washington, D.C.)</jtitle><addtitle>J. Nat. Prod</addtitle><date>2003-07-01</date><risdate>2003</risdate><volume>66</volume><issue>7</issue><spage>917</spage><epage>921</epage><pages>917-921</pages><issn>0163-3864</issn><eissn>1520-6025</eissn><coden>JNPRDF</coden><abstract>Five novel (22R,23S,24S)-steroids, hippuristerones E-I (1-5), have been isolated from the gorgonian coral Isis hippuris. The structures of steroids 1-5 were deduced by extensive 1D and 2D NMR studies ((1)H, (13)C, (1)H-(1)H COSY, HMQC, HMBC, and NOESY experiments). The structure of 1 was further supported by molecular mechanics calculations.</abstract><cop>Washington, DC</cop><cop>Glendale, AZ</cop><pub>American Chemical Society</pub><pmid>12880306</pmid><doi>10.1021/np020602r</doi><tpages>5</tpages></addata></record> |
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| subjects | Analytical, structural and metabolic biochemistry Animals Anthozoa - chemistry biochemical pathways Biological and medical sciences biosynthesis carbon chemical structure corals Fundamental and applied biological sciences. Psychology hippuristerones Isis hippuris methine methylene Molecular Conformation Molecular Structure Nuclear Magnetic Resonance, Biomolecular Other biological molecules Oxygen - chemistry protons spectral analysis stereochemistry steroids Steroids - chemistry Steroids - isolation & purification Taiwan Terpenes, steroids. Hormones |
| title | Hippuristerones E-I, new polyoxygenated steroids from the gorgonian coral Isis hippuris |
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