Image analysis to quantify S100-positive dendritic cells in leprosy-affected skin

Image analysis to quantify S100-positive dendritic cells in leprosy-affected skin

A morphometric analysis of skin dendritic cells was done on biopsies of patients with different forms of leprosy. An anti S100 antibody was used to determine dendritic cell quantity and extension. Patients with a better immune response to the bacillus showed a greater number of dendritic cells in th...

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Veröffentlicht in:Biomédica 2003-06, Vol.23 (2), p.131-133
Hauptverfasser: Camargo, Luz H, Caldas, María Leonor, Neira, Marcela, Sarmiento, Ladys
Format: Artikel
Sprache:spa
Schlagworte:
Dendritic Cells - immunology
Humans
Image Processing, Computer-Assisted - methods
Leprosy - immunology
Leprosy - pathology
S100 Proteins - analysis
S100 Proteins - immunology
Skin - immunology
Skin - pathology
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Zusammenfassung:A morphometric analysis of skin dendritic cells was done on biopsies of patients with different forms of leprosy. An anti S100 antibody was used to determine dendritic cell quantity and extension. Patients with a better immune response to the bacillus showed a greater number of dendritic cells in the cases of dimorphic tuberculoid leprosy and tuberculoid leprosy. This result contrasted with that from patients with dimorphic lepromatous leprosy and lepromatous leprosy.
ISSN:0120-4157