D-dimer, inflammatory markers, and lower extremity functioning in patients with and without peripheral arterial disease

We determined whether higher levels of D-dimer, C-reactive protein (CRP), fibrinogen, and serum amyloid A are associated independently with functional impairment in patients with and without peripheral arterial disease (PAD). Participants were 370 men and women with PAD (ankle brachial index

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Bibliographische Detailangaben
Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 2003-07, Vol.107 (25), p.3191-3198
Hauptverfasser:	MCDERMOTT, Mary Mcgrae, GREENLAND, Philip, SCHNEIDER, Joseph R, MARTIN, Gary, RIFAI, Nader, QUANN, Maureen, FORNAGE, Myriam, GREEN, David, GURALNIK, Jack M, CRIQUI, Michael H, KIANG LIU, CHEELING CHAN, PEARCE, William H, TAYLOR, Lloyd, RIDKER, Paul M
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Ankle - blood supply Ankle - physiopathology Biological and medical sciences Biomarkers - analysis Blood and lymphatic vessels Brachial Artery - physiopathology C-Reactive Protein - analysis Cardiology. Vascular system Cohort Studies Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous Exercise Test Female Fibrin Fibrinogen Degradation Products - analysis Fibrinogen - analysis Humans Lower Extremity - blood supply Lower Extremity - physiopathology Male Medical sciences Middle Aged Peripheral Vascular Diseases - blood Peripheral Vascular Diseases - diagnosis Peripheral Vascular Diseases - physiopathology Predictive Value of Tests Serum Amyloid A Protein - analysis Walking
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Beschreibung
Zusammenfassung:	We determined whether higher levels of D-dimer, C-reactive protein (CRP), fibrinogen, and serum amyloid A are associated independently with functional impairment in patients with and without peripheral arterial disease (PAD). Participants were 370 men and women with PAD (ankle brachial index
ISSN:	0009-7322 1524-4539
DOI:	10.1161/01.CIR.0000074227.53616.CC