Effectiveness of sirolimus-eluting stent implantation for recurrent in-stent restenosis after brachytherapy

This report evaluated sirolimus-eluting stent implantation to treat recurrent in-stent restenosis after failed brachytherapy in 12 consecutive patients. This strategy appeared to be safe and clinically effective, although the high rate of angiographic restenosis observed suggests a reduced efficacy...

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Veröffentlicht in:The American journal of cardiology 2003-07, Vol.92 (2), p.200-203
Hauptverfasser: Saia, Francesco, Lemos, Pedro A., Sianos, Georgios, Degertekin, Muzaffer, Lee, Chi-Hang, Arampatzis, Chourmouzios A., Hoye, Angela, Tanabe, Kengo, Regar, Evelyn, van der Giessen, Willem J., Smits, Pieter C., de Feyter, Pim, Ligthart, Jurghen, van Domburg, Ron T., Serruys, Patrick W.
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container_end_page 203
container_issue 2
container_start_page 200
container_title The American journal of cardiology
container_volume 92
creator Saia, Francesco
Lemos, Pedro A.
Sianos, Georgios
Degertekin, Muzaffer
Lee, Chi-Hang
Arampatzis, Chourmouzios A.
Hoye, Angela
Tanabe, Kengo
Regar, Evelyn
van der Giessen, Willem J.
Smits, Pieter C.
de Feyter, Pim
Ligthart, Jurghen
van Domburg, Ron T.
Serruys, Patrick W.
description This report evaluated sirolimus-eluting stent implantation to treat recurrent in-stent restenosis after failed brachytherapy in 12 consecutive patients. This strategy appeared to be safe and clinically effective, although the high rate of angiographic restenosis observed suggests a reduced efficacy of rapamycin to prevent neointimal hyperplasia in this setting compared with the treatment of de novo lesions.
doi_str_mv 10.1016/S0002-9149(03)00538-1
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subjects Aged
Biological and medical sciences
Blood Vessel Prosthesis Implantation
Brachytherapy
Cardiovascular disease
Diseases of the cardiovascular system
Effectiveness
Female
Follow-Up Studies
Graft Occlusion, Vascular - drug therapy
Graft Occlusion, Vascular - prevention & control
Graft Occlusion, Vascular - radiotherapy
Humans
Immunosuppressive Agents - administration & dosage
Immunosuppressive Agents - therapeutic use
Male
Medical sciences
Middle Aged
Outcome Assessment (Health Care)
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Secondary Prevention
Sirolimus - administration & dosage
Sirolimus - therapeutic use
Stents
Treatment Failure
title Effectiveness of sirolimus-eluting stent implantation for recurrent in-stent restenosis after brachytherapy
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