Effectiveness of sirolimus-eluting stent implantation for recurrent in-stent restenosis after brachytherapy

This report evaluated sirolimus-eluting stent implantation to treat recurrent in-stent restenosis after failed brachytherapy in 12 consecutive patients. This strategy appeared to be safe and clinically effective, although the high rate of angiographic restenosis observed suggests a reduced efficacy...

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Veröffentlicht in:	The American journal of cardiology 2003-07, Vol.92 (2), p.200-203
Hauptverfasser:	Saia, Francesco, Lemos, Pedro A., Sianos, Georgios, Degertekin, Muzaffer, Lee, Chi-Hang, Arampatzis, Chourmouzios A., Hoye, Angela, Tanabe, Kengo, Regar, Evelyn, van der Giessen, Willem J., Smits, Pieter C., de Feyter, Pim, Ligthart, Jurghen, van Domburg, Ron T., Serruys, Patrick W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biological and medical sciences Blood Vessel Prosthesis Implantation Brachytherapy Cardiovascular disease Diseases of the cardiovascular system Effectiveness Female Follow-Up Studies Graft Occlusion, Vascular - drug therapy Graft Occlusion, Vascular - prevention & control Graft Occlusion, Vascular - radiotherapy Humans Immunosuppressive Agents - administration & dosage Immunosuppressive Agents - therapeutic use Male Medical sciences Middle Aged Outcome Assessment (Health Care) Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Secondary Prevention Sirolimus - administration & dosage Sirolimus - therapeutic use Stents Treatment Failure
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Beschreibung
Zusammenfassung:	This report evaluated sirolimus-eluting stent implantation to treat recurrent in-stent restenosis after failed brachytherapy in 12 consecutive patients. This strategy appeared to be safe and clinically effective, although the high rate of angiographic restenosis observed suggests a reduced efficacy of rapamycin to prevent neointimal hyperplasia in this setting compared with the treatment of de novo lesions.
ISSN:	0002-9149 1879-1913
DOI:	10.1016/S0002-9149(03)00538-1