A New Azoxyalkene from a Strain of an Actinomadura-Like Fungus

Abstract A new proximal α,β-(CIS)-unsaturated azoxyalkene (1) was produced by a fungal strain named A7, identified as ACTINOMADURA sp., isolated from apricot (PRUNUS ARMENIACA) roots. Compound 1 was isolated together with the polyene macrolide fungichromine, and its structure and geometry were estab...

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Veröffentlicht in:	Planta medica 2003-06, Vol.69 (6), p.574-576
Hauptverfasser:	Bianchi, Giulia, Dallavalle, Sabrina, Merlini, Lucio, Nasini, Gianluca, Quaroni, Sergio
Format:	Artikel
Sprache:	eng
Schlagworte:	Actinomycetales Anti-Bacterial Agents Anti-Infective Agents - chemistry Anti-Infective Agents - pharmacology Biological and medical sciences General pharmacology Humans Letter Medical sciences Microbial Sensitivity Tests Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Phytotherapy Plant Roots Prunus - microbiology Rhodotorula - drug effects
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Zusammenfassung:	Abstract A new proximal α,β-(CIS)-unsaturated azoxyalkene (1) was produced by a fungal strain named A7, identified as ACTINOMADURA sp., isolated from apricot (PRUNUS ARMENIACA) roots. Compound 1 was isolated together with the polyene macrolide fungichromine, and its structure and geometry were established mainly by UV, MS and 1 H- and 13 C-NMR mono-dimensional and two-dimensional experiments. Compound 1 showed a weak antibiotic activity against RHODOTORULA sp.
ISSN:	0032-0943 1439-0221
DOI:	10.1055/s-2003-40633