Successful liver transplantation in a patient with sickle-cell anaemia

Liver transplantation in the setting of sickle-cell anaemia poses several new challenges to the transplant team. Hypoxaemia, acidosis and a decrease in body temperature are common occurrences that can cause sickling in the peri-operative period, putting the patient at risk of sickle-cell crises or g...

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Veröffentlicht in:Transplant international 2003-06, Vol.16 (6), p.434-436
Hauptverfasser: VAN DEN HAZEL, Sven J, METSELAAR, Herold J, TILANUS, Hugo W, IJZERMANS, Jan N, GROENLAND, Theo H. N, VISSER, Loes, DE MAN, Robert A
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Sprache:eng
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Zusammenfassung:Liver transplantation in the setting of sickle-cell anaemia poses several new challenges to the transplant team. Hypoxaemia, acidosis and a decrease in body temperature are common occurrences that can cause sickling in the peri-operative period, putting the patient at risk of sickle-cell crises or graft dysfunction. We describe a patient with sickle-cell anaemia who successfully underwent transplantation, and we discuss the rationale of various precautions that had to be taken.
ISSN:0934-0874
1432-2277
DOI:10.1007/s00147-003-0567-5