The IgA receptor complex: a two-for-one deal
IgA triggers immune responses by binding to Fc receptors on cells of the immune system. The structure of IgA1-Fc in a complex with two molecules of FcαRI provides clues that may explain the selectivity of IgA-mediated immune events.
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Veröffentlicht in: | Nature structural & molecular biology 2003-08, Vol.10 (8), p.585-587 |
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creator | Wurzburg, Beth A Jardetzky, Theodore S |
description | IgA triggers immune responses by binding to Fc receptors on cells of the immune system. The structure of IgA1-Fc in a complex with two molecules of FcαRI provides clues that may explain the selectivity of IgA-mediated immune events. |
doi_str_mv | 10.1038/nsb0803-585 |
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subjects | Biochemistry Biological Microscopy Biomedical and Life Sciences Humans Immunoglobulin A - chemistry Immunoglobulin A - metabolism Life Sciences Macromolecular Substances Membrane Biology Models, Molecular news-and-views Protein Structure Receptors, Fc - chemistry Receptors, Fc - metabolism Receptors, IgE - chemistry Receptors, IgE - metabolism Receptors, IgG - chemistry Receptors, IgG - metabolism |
title | The IgA receptor complex: a two-for-one deal |
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