Increased Interleukin-6 Activity in Cardiac Myxoma with Mediastinal Lymphadenopathy

We report a case of cardiac myxoma with mediastinal lymphadenopathy which seems to be a very rare feature. Laboratory examination revealed high level of interleukin-6 (IL-6) activity in serum. Interestingly, after removal of cardiac myxoma, mediastinal lymphadenopathy disappeared on the chest CT and...

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Veröffentlicht in:	Internal Medicine 1992, Vol.31(10), pp.1207-1209
Hauptverfasser:	KUROKI, Shigetaka, NAITOH, Keiko, KATOH, Osamu, YAMADA, Hozumi, ITOH, Tsuyoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Cardiac myxoma Castleman's disease Female Heart Neoplasms - complications Heart Neoplasms - metabolism Heart Neoplasms - surgery Humans IL-6 Interleukin-6 - biosynthesis Lymph Nodes - pathology lymphadenopathy Lymphatic Diseases - etiology Mediastinal Diseases - etiology Middle Aged Myxoma - complications Myxoma - metabolism Myxoma - surgery Tomography, X-Ray Computed
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Beschreibung
Zusammenfassung:	We report a case of cardiac myxoma with mediastinal lymphadenopathy which seems to be a very rare feature. Laboratory examination revealed high level of interleukin-6 (IL-6) activity in serum. Interestingly, after removal of cardiac myxoma, mediastinal lymphadenopathy disappeared on the chest CT and the level of serum IL-6 was decreased. These findings suggest that IL-6 which was probably derived from myxoma, may have played an important role in the development of lymphadenopathy. (Internal Medicine 31 : 1207-1209, 1992)
ISSN:	0918-2918 1349-7235
DOI:	10.2169/internalmedicine.31.1207