Isolation and characterization of macrocarpals B-G antibacterial compounds from Eucalyptus macrocarpa

Six novel phloroglucinol dialdehyde diterpene derivatives (macrocarpals B-G), which have antibacterial activity, were isolated from leaves of Eucalyptus macrocarpa. These compounds have closely related structures, the molecular formula for B-F being C 28 H 40 O 6 , and that of G being C 28 H 38 O 5...

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Veröffentlicht in:	Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 1992-01, Vol.56 (10), p.1570-1576
Hauptverfasser:	Yamakoshi, Y. (Ochanomizu Univ., Tokyo (Japan)), Murata, M, Shimizu, A, Homma, S
Format:	Artikel
Sprache:	eng
Schlagworte:	ACIDE PHENOLIQUE ACIDOS FENOLICOS ALDEHIDOS ALDEHYDE ALDEHYDES Anti-Bacterial Agents - isolation & purification Anti-Bacterial Agents - pharmacology Bacillus subtilis - drug effects BACTERICIDAS BACTERICIDE BACTERICIDES Biological and medical sciences Biotechnology Chemical constitution CHEMICAL STRUCTURE Diterpenes - isolation & purification Diterpenes - pharmacology DITERPENOIDE DITERPENOIDS DITERPENOS ESTRUCTURA QUIMICA EUCALYPTUS Eucalyptus - chemistry Fundamental and applied biological sciences. Psychology Magnetic Resonance Spectroscopy - methods Microbial Sensitivity Tests Molecular Structure PHENOLIC ACIDS Phloroglucinol - analogs & derivatives Phloroglucinol - isolation & purification Phloroglucinol - pharmacology Plant Extracts - isolation & purification Plant Extracts - pharmacology Plant physiology and development Plants, Medicinal Spectrophotometry, Ultraviolet Staphylococcus aureus - drug effects STRUCTURE CHIMIQUE
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Zusammenfassung:	Six novel phloroglucinol dialdehyde diterpene derivatives (macrocarpals B-G), which have antibacterial activity, were isolated from leaves of Eucalyptus macrocarpa. These compounds have closely related structures, the molecular formula for B-F being C 28 H 40 O 6 , and that of G being C 28 H 38 O 5 . The structures of macrocarpals B, D, and G were analyzed by means of NMR analyses.
ISSN:	0916-8451 1347-6947
DOI:	10.1271/bbb.56.1570