The molecular biology of the porcine paramyxovirus LPMV

Protein and genomic studies of a previously uncharacterized porcine paramyxovirus (designated LPMV) confirmed that it was a member of the paramyxovirus genus. The nucleotide sequences and deduced amino acids of the complete P-gene, M-gene, F-gene and HN-gene as well as the intergenic sequences have...

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Veröffentlicht in:Veterinary microbiology 1992-11, Vol.33 (1), p.263-273
Hauptverfasser: Linné, Tommy, Berg, Mikael, Bergvall, Ann-Christin, Hjertner, Bernt, Moreno-López, Jorge
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container_end_page 273
container_issue 1
container_start_page 263
container_title Veterinary microbiology
container_volume 33
creator Linné, Tommy
Berg, Mikael
Bergvall, Ann-Christin
Hjertner, Bernt
Moreno-López, Jorge
description Protein and genomic studies of a previously uncharacterized porcine paramyxovirus (designated LPMV) confirmed that it was a member of the paramyxovirus genus. The nucleotide sequences and deduced amino acids of the complete P-gene, M-gene, F-gene and HN-gene as well as the intergenic sequences have been determined. Comparative sequence analysis of the M-gene of LPMV revealed the closest relationship of LPMV was to human mumps virus with a homology of 46% and 55% at the amino acid and nucleotide levels respectively. The P-gene of LPMV is transcribed to V protein mRNA and by editing of the gene to the P protein mRNA. The LPMV P-gene has the coding capacity for an additional protein of 126 amino acids, a C protein.
doi_str_mv 10.1016/0378-1135(92)90054-W
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source MEDLINE; Elsevier ScienceDirect Journals
subjects Amino Acid Sequence
Animals
Base Sequence
Biological and medical sciences
CERDO
Fundamental and applied biological sciences. Psychology
GENE
GENES
Genetics
Genome, Viral
Microbiology
Molecular Sequence Data
NUCLEOTIDE SEQUENCE
PARAMYXOVIRIDAE
Paramyxoviridae - classification
Paramyxoviridae - genetics
Paramyxoviridae - ultrastructure
PORCIN
Respirovirus Infections - microbiology
Respirovirus Infections - veterinary
RNA, Viral - chemistry
SECUENCIA NUCLEICA
SEQUENCE NUCLEIQUE
SWINE
Swine Diseases - microbiology
Viral Proteins - chemistry
Viral Proteins - genetics
Virology
title The molecular biology of the porcine paramyxovirus LPMV
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