PPAR-γ expression in peritoneal endometriotic lesions correlates with pain experienced by patients

Endometriosis is a significant gynecologic condition that can cause both pain and infertility and affects up to 15% of women during their reproductive years. In peritoneal endometriotic lesions, the expression of peroxisome proliferation–activated receptor gamma, a nuclear receptor with antiinflamma...

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Veröffentlicht in:	Fertility and sterility 2010, Vol.93 (1), p.293-296
Hauptverfasser:	McKinnon, Brett, Ph.D, Bersinger, Nick A., Ph.D, Huber, Alexander W., M.D, Kuhn, Annette, M.D, Mueller, Michael D., M.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Dysmenorrhea - etiology Dysmenorrhea - metabolism Dyspareunia - etiology Dyspareunia - metabolism Endometriosis - complications Endometriosis - metabolism Endometriosis - surgery Female Female genital diseases Gynecology. Andrology. Obstetrics Humans Immunohistochemistry Internal Medicine Laparoscopy Medical sciences Non tumoral diseases Obstetrics and Gynecology Pain Measurement Pelvic Pain - etiology Pelvic Pain - metabolism Peritoneal Diseases - complications Peritoneal Diseases - metabolism Peritoneal Diseases - surgery PPAR gamma - analysis Severity of Illness Index
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Beschreibung
Zusammenfassung:	Endometriosis is a significant gynecologic condition that can cause both pain and infertility and affects up to 15% of women during their reproductive years. In peritoneal endometriotic lesions, the expression of peroxisome proliferation–activated receptor gamma, a nuclear receptor with antiinflammatory and neuroprotective roles, is positively correlated with the pain reported by patients.
ISSN:	0015-0282 1556-5653
DOI:	10.1016/j.fertnstert.2009.07.980