Control of breathing in children with mild sleep apnoea: a 6-year follow-up study

We have previously shown that children (average age 9 yrs) with mildly elevated obstructive apnoea/hypopnoea indices (OAHI) retained CO(2) at rest. Here, we report the results of a 6-yr follow-up study on 14 children from that study. Minute ventilation (V'(E)) and end-tidal CO(2) partial pressu...

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Veröffentlicht in:	The European respiratory journal 2010-01, Vol.35 (1), p.124-131
Hauptverfasser:	Rice, A, Costy-Bennett, S, Goodwin, J. L, Quan, S. F, Fregosi, R. F
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Biological and medical sciences Breath Tests Carbon Dioxide - analysis Child Female Follow-Up Studies Humans Male Medical sciences Pneumology Respiration Respiratory system : syndromes and miscellaneous diseases Severity of Illness Index Sleep Apnea Syndromes - physiopathology Time Factors
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Zusammenfassung:	We have previously shown that children (average age 9 yrs) with mildly elevated obstructive apnoea/hypopnoea indices (OAHI) retained CO(2) at rest. Here, we report the results of a 6-yr follow-up study on 14 children from that study. Minute ventilation (V'(E)) and end-tidal CO(2) partial pressure (P(ET,CO(2))) were measured during hypercapnic challenge. OAHI decreased from 7.5+/-4.7 events x h(-1) at age 9 yrs to 2.5+/-1.8 events x h(-1) at age 15 yrs (p
ISSN:	0903-1936 1399-3003
DOI:	10.1183/09031936.00178408