Regional Very Low Cerebral Blood Volume Predicts Hemorrhagic Transformation Better Than Diffusion-Weighted Imaging Volume and Thresholded Apparent Diffusion Coefficient in Acute Ischemic Stroke

Currently, diffusion-weighted imaging (DWI) lesion volume is the most useful magnetic resonance imaging predictor of hemorrhagic transformation (HT). Preliminary studies have suggested that very low cerebral blood volume (VLCBV) predicts HT. We compared HT prediction by VLCBV and DWI using data from...

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Veröffentlicht in:	Stroke (1970) 2010, Vol.41 (1), p.82-88
Hauptverfasser:	CAMPBELL, Bruce C. V, CHRISTENSEN, Søren, DONNAN, Geoffrey A, DAVIS, Stephen M, BUTCHER, Kenneth S, GORDON, Ian, PARSONS, Mark W, DESMOND, Patricia M, BARBER, P. Alan, LEVI, Christopher R, BLADIN, Christopher F, DE SILVA, Deidre A
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Biological and medical sciences Blood Volume - physiology Brain Ischemia - diagnosis Brain Ischemia - physiopathology Cerebral Hemorrhage - diagnosis Cerebral Hemorrhage - physiopathology Cerebrovascular Circulation - physiology Diffusion Magnetic Resonance Imaging Double-Blind Method Female Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Humans Male Medical sciences Nervous system (semeiology, syndromes) Neurology Predictive Value of Tests Prospective Studies Stroke - diagnosis Stroke - physiopathology Vascular diseases and vascular malformations of the nervous system
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Zusammenfassung:	Currently, diffusion-weighted imaging (DWI) lesion volume is the most useful magnetic resonance imaging predictor of hemorrhagic transformation (HT). Preliminary studies have suggested that very low cerebral blood volume (VLCBV) predicts HT. We compared HT prediction by VLCBV and DWI using data from the EPITHET study. Normal-percentile CBV values were calculated from the nonstroke hemisphere. Whole-brain masks with CBV thresholds of the
ISSN:	0039-2499 1524-4628
DOI:	10.1161/strokeaha.109.562116