The kinin antagonist hoe 140 reduces acute paw oedema in rats caused by carrageenan, bradykinin and kaolin

The kinin antagonist hoe 140 reduces acute paw oedema in rats caused by carrageenan, bradykinin and kaolin

The present study aimed to evaluate the effect of Hoe 140, a BK receptor B(2) antagonist, on acute oedema induced by carrageenan, BK and kaolin in male Wistar Kyoto rats. Hoe 140 (0.2 mg/kg and 20 mg/kg) given ip caused significant (p

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Veröffentlicht in:Inflammopharmacology 1998, Vol.6 (1), p.9-17
Hauptverfasser: Sharma, J N, Yusof, A P, Wirth, K J
Format: Artikel
Sprache:eng
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Zusammenfassung:The present study aimed to evaluate the effect of Hoe 140, a BK receptor B(2) antagonist, on acute oedema induced by carrageenan, BK and kaolin in male Wistar Kyoto rats. Hoe 140 (0.2 mg/kg and 20 mg/kg) given ip caused significant (p
ISSN:0925-4692
1568-5608
DOI:10.1007/s10787-998-0002-8