Increasing the hydrophobicity and electrospray response of glycans through derivatization with novel cationic hydrazides

Increasing the hydrophobicity and electrospray response of glycans through derivatization with novel cationic hydrazides

Novel tags are used to increase the hydrophobicity of glycans and impart a permanent charge yielding as great as a approximately 5-fold increase in electrospray response from both a standard and complex mixture.

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2010-01, Vol.46 (2), p.237-239
Hauptverfasser: Bereman, Michael S, Comins, Daniel L, Muddiman, David C
Format: Artikel
Sprache:eng
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Zusammenfassung:Novel tags are used to increase the hydrophobicity of glycans and impart a permanent charge yielding as great as a approximately 5-fold increase in electrospray response from both a standard and complex mixture.
ISSN:1359-7345
1364-548X
DOI:10.1039/b915589a