Influence of plasma exchange on the disposition of the fourth generation cephalosporin cefepime

Cefepime, a fourth generation cephalosporin, is widely used in hematology and oncology patients. These patients may require plasma exchange (PE) for indications such as chemotherapy- or cancer-induced thromobotic thrombocytopenic purpura to name a few. To date, no pharmacokinetic evaluation has been...

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Veröffentlicht in:	Journal of oncology pharmacy practice 2009-12, Vol.15 (4), p.217-222
Hauptverfasser:	Ibrahim, Rami B, Liu, Chin Y, Cronin, Simon M, Murphy, Bridgette C, Cha, Raymond, Swerdlow, Paul, Avila, Tomoco, Smith, Stephen T, Lewis, Richard A, Edwards, David J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Anti-Infective Agents - administration & dosage Anti-Infective Agents - adverse effects Anti-Infective Agents - pharmacokinetics Bioavailability Cephalosporins - administration & dosage Cephalosporins - adverse effects Cephalosporins - pharmacokinetics Chemotherapy Chromatography, High Pressure Liquid Creatinine - metabolism Drug dosages Female Humans Injections, Intravenous Male Middle Aged Neoplasms - complications Neoplasms - metabolism Pharmacology Plasma Plasma Exchange - adverse effects Plasmapheresis
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