Stimulation of indole alkaloid content in vanadium-treated Catharanthus roseus suspension cultures

Abstract Addition of vanadyl sulphate to cell suspensions of CATHARANTHUS ROSEUS was found to increase ajmalicine, catharanthine, and tryptamine levels. Up to 500 µg/g dry weight catharanthine and 131.0 µg/g dry weight ajmalicine were detected in vanadyl sulphate-treated cells. This represents an ap...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Planta medica 1988-04, Vol.54 (2), p.149-152
Hauptverfasser:	Tallevi, S.G, DiCosmo, F
Format:	Artikel
Sprache:	eng
Schlagworte:	alkaloids Biological and medical sciences Biotechnology Catharanthus roseus cell suspension culture enzyme activity Eukaryotic cell cultures Fundamental and applied biological sciences. Psychology Health. Pharmaceutical industry indoles Industrial applications and implications. Economical aspects Methods. Procedures. Technologies Miscellaneous Plant cells and fungal cells vanadium
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Abstract Addition of vanadyl sulphate to cell suspensions of CATHARANTHUS ROSEUS was found to increase ajmalicine, catharanthine, and tryptamine levels. Up to 500 µg/g dry weight catharanthine and 131.0 µg/g dry weight ajmalicine were detected in vanadyl sulphate-treated cells. This represents an approximate increase of 50% over control levels. This stimulation was found to be dependent upon the concentration of vanadyl sulphate administered and upon the cell age. High tryptamine levels were not correlated with increased tryptophan decarboxylase activity. Vanadium content of the cells was found to reach a maximum within 1 min following vanadyl sulphate treatment as measured by Instrumental Neutron Activation Analysis.
ISSN:	0032-0943 1439-0221
DOI:	10.1055/s-2006-962374