Acryloyl Chloride: An Excellent Substrate for Cross-Metathesis. A One-Pot Sequence for the Synthesis of Substituted α,β-Unsaturated Carbonyl Derivatives
A diverse set of functionalized α,β-unsaturated carbonyl compounds were synthesized in good yield by utilizing a very simple one-pot process involving a cross-metathesis between acryloyl chloride and a terminal olefin followed by the addition of a nucleophile.
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Veröffentlicht in: | Organic letters 2009-12, Vol.11 (23), p.5446-5448 |
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Hauptverfasser: | , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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Zusammenfassung: | A diverse set of functionalized α,β-unsaturated carbonyl compounds were synthesized in good yield by utilizing a very simple one-pot process involving a cross-metathesis between acryloyl chloride and a terminal olefin followed by the addition of a nucleophile. |
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ISSN: | 1523-7060 1523-7052 |
DOI: | 10.1021/ol9021386 |