Acryloyl Chloride: An Excellent Substrate for Cross-Metathesis. A One-Pot Sequence for the Synthesis of Substituted α,β-Unsaturated Carbonyl Derivatives

A diverse set of functionalized α,β-unsaturated carbonyl compounds were synthesized in good yield by utilizing a very simple one-pot process involving a cross-metathesis between acryloyl chloride and a terminal olefin followed by the addition of a nucleophile.

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Veröffentlicht in:Organic letters 2009-12, Vol.11 (23), p.5446-5448
Hauptverfasser: Ferrié, Laurent, Bouzbouz, Samir, Cossy, Janine
Format: Artikel
Sprache:eng
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Zusammenfassung:A diverse set of functionalized α,β-unsaturated carbonyl compounds were synthesized in good yield by utilizing a very simple one-pot process involving a cross-metathesis between acryloyl chloride and a terminal olefin followed by the addition of a nucleophile.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol9021386