Isolation and identification of a new antifungal sesquiterpene lactone from Inula viscosa

Isolation and identification of a new antifungal sesquiterpene lactone from Inula viscosa

Abstract A new sesquiterpene - tayunin - has been isolated and purified from powdered leaves of INULA VISCOSA (L.) Ait. The chemical structure was determined by 1D and 2D NMR analysis, and IR and MS. Tayunin inhibits the growth of MICROSPORUM CANIS at a concentration of 10 µg/ml and TRICHOPHYTON RUB...

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Veröffentlicht in:Planta medica 1999-04, Vol.65 (3), p.281-282
Hauptverfasser: Maoz, M, Kashman, Y, Neeman, I
Format: Artikel
Sprache:eng
Schlagworte:
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antifungal agents
antifungal properties
Biological and medical sciences
chemical constituents of plants
chemical structure
Dittrichia viscosa
dosage
General pharmacology
leaves
Letter
Medical sciences
Microsporum canis
nuclear magnetic resonance spectroscopy
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
sesquiterpenoid lactones
spectral analysis
Trichophyton rubrum
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Zusammenfassung:Abstract A new sesquiterpene - tayunin - has been isolated and purified from powdered leaves of INULA VISCOSA (L.) Ait. The chemical structure was determined by 1D and 2D NMR analysis, and IR and MS. Tayunin inhibits the growth of MICROSPORUM CANIS at a concentration of 10 µg/ml and TRICHOPHYTON RUBRUM at 50 µg/ml(MIC).
ISSN:0032-0943
1439-0221
DOI:10.1055/s-2006-960780