Practical application to time indicator of a novel white film formed by interaction of calcium salts with hydroxypropyl methylcellulose

We have found that a cast film forms a white film when an aqueous solution comprising hydroxypropyl methylcellulose (HPMC) and calcium salts such as calcium lactate pentahydrate (CLP) and calcium chloride (CaCl 2) is used. In contrast, the obtained white film was transformed into a transparent film...

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Veröffentlicht in:International journal of pharmaceutics 2010-01, Vol.383 (1), p.255-263
Hauptverfasser: Shiraishi, Sumihiro, Sakata, Yukoh, Yamaguchi, Hiroyuki
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Sprache:eng
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