Chiral 1,1′-binaphthylazepine-derived amino alcohol catalyzed asymmetric aryl transfer reactions with boroxine as aryl source

Using chiral 1,1′‐binaphthylazepine‐derived amino alcohol as catalyst, the direct addition of in situ prepared arylzinc (with triphenylboroxine as aryl source) to various aryl aldehydes can afford optically active diarylmethanols in high yields and enantioselectivities (up to 96%). Chirality, 2010....

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Chirality (New York, N.Y.) N.Y.), 2010-01, Vol.22 (1), p.159-164
Hauptverfasser:	Liu, Can, Guo, Zong-Liang, Weng, Jiang, Lu, Gui, Chan, Albert S. C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohols Aldehydes amino alcohol Amino Alcohols - chemistry Aromatic compounds aryl transfer reaction Asymmetry Azepines - chemistry Boron Compounds - chemistry boroxine Catalysis Catalysts Chirality Chromatography, High Pressure Liquid diarylmethanol Magnetic Resonance Spectroscopy Naphthalenes - chemistry Optical activity Reproduction Spectrometry, Mass, Electrospray Ionization Stereoisomerism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Using chiral 1,1′‐binaphthylazepine‐derived amino alcohol as catalyst, the direct addition of in situ prepared arylzinc (with triphenylboroxine as aryl source) to various aryl aldehydes can afford optically active diarylmethanols in high yields and enantioselectivities (up to 96%). Chirality, 2010. © 2009 Wiley‐Liss, Inc.
ISSN:	0899-0042 1520-636X
DOI:	10.1002/chir.20721