CTLA4 exon 1 and promoter polymorphisms in patients with multiple sclerosis

Objective – The polymorphisms of exon 1 (+49 A/G) and promoter regions (−1722 T/C, −1661 A/G and −318 C/T)of cytotoxic T lymphocyte antigen 4 (CTLA4) and also haplotypes constructed from mentioned loci were investigated amongst 153 Iranian patients with definite multiple sclerosis (MS) and 190 heal...

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Veröffentlicht in:	Acta neurologica Scandinavica 2009-12, Vol.120 (6), p.424-429
Hauptverfasser:	Yousefipour, G., Erfani, N., Momtahan, M., Moghaddasi, H., Ghaderi, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	1661 A/G Adult Alleles Antigens, CD - genetics Biological and medical sciences CTLA-4 Antigen cytotoxic T lymphocyte antigen 4 exon 1 Female Gene Frequency Genetic Predisposition to Disease - genetics Genotype haplotype Haplotypes - genetics Human viral diseases Humans Infectious diseases Iran Male Medical sciences multiple sclerosis Multiple Sclerosis - genetics Neurology Patient Selection polymorphism Polymorphism, Single Nucleotide - genetics Promoter Regions, Genetic Viral diseases Viral diseases of the nervous system
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